Use Of Chimeric Antigen Receptor-modified T Cells To Treat Cancer

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Abstract

The present invention provides compositions and methods for treating cancer in a human. The invention includes relates to administering a genetically modified T cell to express a CAR wherein the CAR comprises an antigen binding domain, a transmembrane domain, a costimulatory signaling region, and a CD3 zeta signaling domain.


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Document History
  • Publication: Sep 6, 2017
  • Application: Dec 9, 2011
    EP EP 17153799 A
  • Priority: Dec 9, 2011
    EP EP 11846757 A
  • Priority: Dec 9, 2011
    US US 2011/0064191 W
  • Priority: Jun 29, 2011
    US US 201161502649 P
  • Priority: Dec 9, 2010
    US US 42147010 P

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