{"search_session":{},"preferences":{"l":"en","queryLanguage":"en"},"patentId":"EP_3181697_A1","frontPageModel":{"patentViewModel":{"ref":{"entityRefType":"PATENT","entityRefId":"029-829-705-759-226"},"entityMetadata":{"linkedIds":{"empty":true},"tags":[],"collections":[{"id":11849,"type":"PATENT","title":"University of Liege Patent Portfolio","description":"","access":"OPEN_ACCESS","displayAvatar":true,"attested":false,"itemCount":6891,"tags":[],"user":{"id":91044780,"username":"Cambialens","firstName":"","lastName":"","created":"2015-05-04T00:55:26.000Z","displayName":"Cambialens","preferences":"{\"usage\":\"public\",\"beta\":false}","accountType":"PERSONAL","isOauthOnly":false},"notes":[{"id":8461,"type":"COLLECTION","user":{"id":91044780,"username":"Cambialens","firstName":"","lastName":"","created":"2015-05-04T00:55:26.000Z","displayName":"Cambialens","preferences":"{\"usage\":\"public\",\"beta\":false}","accountType":"PERSONAL","isOauthOnly":false},"text":"
Search Applicants and Owners separately:univ* AND Liege. Select more for logical variants. Add to collection. Select all patents in the collection and expand by simple families. Add to collection. Total patents: 1416
Search Applicants and Owners separately:univ* AND Liege. Select more for logical variants. Add to collection. Select all patents in the collection and expand by simple families. Add to collection. Total patents: 1416
a. obtaining a sample of material containing said genomic DNA from the bovine,
b. extracting the DNA from said sample,
c. genotyping said DNA for the CD mutation, i.e. a 7.5 Kb insertion of a BoERV element in exon 5 of the APOB gene, and
d. determining whether said animal carries the CD mutation."],"number":1,"annotation":false,"title":false,"claim":true},{"lines":["A method for determining whether a bovine is affected by or a carrier of Cholesterol Deficiency by analyzing its RNA, the method comprising the steps of :
a. obtaining a sample of biological material containing said RNA from the bovine,
b. extracting the RNA from said sample,
c. genotyping said DNA for the CD mutation, i.e. a 7 Kb insertion of a BoERV element in exon 5 of the APOB gene, and
d. determining whether said animal carries the CD mutation."],"number":2,"annotation":false,"title":false,"claim":true},{"lines":["A method for determining whether a bovine is a carrier of Cholesterol Deficiency by analyzing its DNA, the method comprising the steps of:
a. obtaining a sample of material containing said genomic DNA from the bovine,
b. extracting the DNA from said sample,
c. genotyping said DNA for genetic markers that are linked to the CD locus,
d. ascertaining whether said animal carries the CD mutation by linkage analysis."],"number":3,"annotation":false,"title":false,"claim":true},{"lines":["A method for determining whether a bovine is a carrier of Cholesterol Deficiency by analyzing its DNA, the method comprising the steps of:
a. obtaining a sample of material containing said genomic DNA from the bovine,
b. extracting the DNA from said sample,
c. genotyping said DNA for genetic markers that are in linkage disequilibrium with the CD locus,
d. ascertaining whether said animal carries the CD mutation by association analysis."],"number":4,"annotation":false,"title":false,"claim":true},{"lines":["The method of any one of claims 1 to 4, wherein the sample is selected from the group consisting of blood, sperm, hair roots, milk, body fluids and/or tissues including nucleated cells."],"number":5,"annotation":false,"title":false,"claim":true},{"lines":["The method of any one of claims 1 to 5, wherein the bovine is selected from the species bos taurus."],"number":6,"annotation":false,"title":false,"claim":true},{"lines":["The method of claim 6 wherein the bovine is selected from the group consisting of Holstein, Friesian and Holstein-Friesian Cross breeds, British and /or Dutch Friesian."],"number":7,"annotation":false,"title":false,"claim":true},{"lines":["Use of the method of any one of claims 1 to 7 to perform marker assisted selection or genomic selection for increased survival in said bovine."],"number":8,"annotation":false,"title":false,"claim":true}]}},"filters":{"npl":[],"notNpl":[],"applicant":[],"notApplicant":[],"inventor":[],"notInventor":[],"owner":[],"notOwner":[],"tags":[],"dates":[],"types":[],"notTypes":[],"j":[],"notJ":[],"fj":[],"notFj":[],"classIpcr":[],"notClassIpcr":[],"classNat":[],"notClassNat":[],"classCpc":[],"notClassCpc":[],"so":[],"notSo":[],"sat":[]},"sequenceFilters":{"s":"SEQIDNO","d":"ASCENDING","p":0,"n":10,"sp":[],"si":[],"len":[],"t":[],"loc":[]}}