Detecting Cholesterol Deficiency Mutation In Cattle


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This invention relates to methods for the detection of bovine that are affected by or carriers of Cholesterol Deficiency (CD). It is based on the identification of a 7 Kb insertion of a BoERVK element in exon 5 of the bovine APOB gene that is causing Cholesterol Deficiency The present invention provides methods for determining whether a bovine is affected by or carrier of CD by analyzing its genomic DNA or its RNA.


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Document History
  • Publication: Jun 21, 2017
  • Application: Dec 14, 2015
    EP EP 15199955 A
  • Priority: Dec 14, 2015
    EP EP 15199955 A

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