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Abstract
The invention provides an immunogenic molecular entity, a supramolecular assembly, and an antibody that can be used to inhibit Gram-positive bacterial quorum sensing, prevent infection or development of a disease condition associated with a Gram-positive bacterial infection. The invention also provides methods of inhibiting Gram-positive bacterial quorum sensing, and methods of preventing infection or development of a disease condition associated with a Gram-positive bacterial infection.
Claims
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Applicants
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Scripps Research Inst
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Inventors
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Janda Kim D
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Kaufmann Gunnar F
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Park Junguk
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CPC Classifications
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A61K47/42
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A61K39/085
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A61K2039/505
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C07K7/64
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C07K16/1271
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C07K16/44
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C07K2317/21
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C07K2317/622
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C07K2317/76
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C07K2317/92
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Document Preview
- Publication: Mar 4, 2015
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Application:
Oct 24, 2008
EP 14180831 A
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Priority:
Oct 24, 2008
EP 08841487 A
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Priority:
Oct 25, 2007
US 98259307 P