Benzoxazepin Pi3k Inhibitor Compounds And Methods Of Use

  • Published: Mar 26, 2014
  • Earliest Priority: Sep 28 2009
  • Family: 64
  • Cited Works: 39
  • Cited by: 0
  • Cites: 9
  • Additional Info: Cited Works Published
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Abstract

The invention relates to benzoxazepin compounds of Formula I including stereoisomers, geometric isomers, tautomers, or pharmaceutically acceptable salts thereof, wherein: Z 1 is CR 1 or N; Z 2 is CR 2 or N; Z 3 is CR 3 or N; Z 4 is CR 4 or N; and B is a pyrazolyl, imidazolyl, or triazolyl ring which compounds have anti-cancer activity, and more specifically, inhibit PI3 kinase activity.


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