{"search_session":{},"preferences":{"l":"en","queryLanguage":"en"},"patentId":"EP_2298340_A1","frontPageModel":{"patentViewModel":{"ref":{"entityRefType":"PATENT","entityRefId":"004-325-132-872-46X"},"entityMetadata":{"linkedIds":{"empty":true},"tags":[],"collections":[{"id":11645,"type":"PATENT","title":"The University of Sheffield - Patent Portfolio","description":"","access":"OPEN_ACCESS","displayAvatar":true,"attested":false,"itemCount":3180,"tags":[],"user":{"id":91044780,"username":"Cambialens","firstName":"","lastName":"","created":"2015-05-04T00:55:26.000Z","displayName":"Cambialens","preferences":"{\"usage\":\"public\",\"beta\":false}","accountType":"PERSONAL","isOauthOnly":false},"notes":[{"id":8311,"type":"COLLECTION","user":{"id":91044780,"username":"Cambialens","firstName":"","lastName":"","created":"2015-05-04T00:55:26.000Z","displayName":"Cambialens","preferences":"{\"usage\":\"public\",\"beta\":false}","accountType":"PERSONAL","isOauthOnly":false},"text":"
Search Applicants and Owners separately:uni* AND Sheffield
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Add to collection. Total patents: 3174
Search Applicants and Owners separately:uni* AND Sheffield
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Select all patents in the collection and expand by simple families.
Add to collection. Total patents: 3174
Group a) at least one staphylococcal extracellular component binding protein or immunogenic fragment thereof selected from the group consisting of SdrG, laminin receptor, SitC/MntC/saliva binding protein, EbhA, EbhB, Elastin binding protein (EbpS), EFB (FIB), SBI, autolysin, ClfA, SdrC, SdrH, Lipase GehD, SasA, FnbA, FnbB, Cna, ClfB, FbpA, Npase, IsaA/PisA, SsaA, EPB, SSP-1, SSP-2, HBP, Vitronectin binding protein, fibrinogen binding protein, coagulase, Fig and MAP;
Group b) at least one staphylococcal transporter protein or immunogenic fragment thereof selected from the group consisting of Immunodominant ABC transporter, IsdA, IsdB, Mg2+ transporter, SitC and Ni ABC transporter;
Group c) at least one staphylococcal regulator of virulence, toxin or immunogenic fragment thereof selected from the group consisting of alpha toxin (Hla), alpha toxin H35R mutant, RNA III activating protein (RAP)."],"number":1,"annotation":false,"title":false,"claim":true},{"lines":["The immunogenic composition of claim 1 wherein at least one protein or immunogenic fragment is selected from group a)."],"number":2,"annotation":false,"title":false,"claim":true},{"lines":["The immunogenic composition of claim 1 or 2 wherein at least one protein or immunogenic fragment is selected from group b)."],"number":3,"annotation":false,"title":false,"claim":true},{"lines":["The immunogenic composition of claims 1-3 wherein at least one protein or immunogenic fragment is selected from group c)."],"number":4,"annotation":false,"title":false,"claim":true},{"lines":["The immunogenic composition of claims 1-4 wherein at least one protein or immunogenic fragment is selected from group a), group b) and group c)."],"number":5,"annotation":false,"title":false,"claim":true},{"lines":["The immunogenic composition of claims 1-5 comprising at least one protein or immunogenic fragment from S. aureus."],"number":6,"annotation":false,"title":false,"claim":true},{"lines":["The immunogenic composition of claims 1-6 comprising at least one protein or immunogenic fragment from S. epidermidis."],"number":7,"annotation":false,"title":false,"claim":true},{"lines":["The immunogenic composition of claims 1-7 further comprising a PIA polysaccharide or oligosaccharide and/or type V and/or type VIII capsular polysaccharide or oligosaccharide from S. aureus."],"number":8,"annotation":false,"title":false,"claim":true},{"lines":["The immunogenic composition of claims 1-8 further comprising Type I, and/or Type II and/or Type III capsular polysaccharide or oligosaccharide from S. epidermidis and/or lipoteichoic acid from a Gram positive bacterium or a staphylococcal bacterium, wherein the lipoteichoic acid is optionally conjugated to a protein carrier."],"number":9,"annotation":false,"title":false,"claim":true},{"lines":["The immunogenic composition of claims 8-9 wherein a staphylococcal capsular polysaccharide is conjugated to a protein carrier."],"number":10,"annotation":false,"title":false,"claim":true},{"lines":["The immunogenic composition of claims 9-10 wherein the protein carrier is selected from the group consisting of tetanus toxoid, diphtheria toxoid, CRM197, Haemophilus influenzae protein D, pneumolysin and alpha toxoid."],"number":11,"annotation":false,"title":false,"claim":true},{"lines":["The immunogenic composition of claims 1-11 wherein an effective immune response is generated against both S.aureus and S. epidermidis."],"number":12,"annotation":false,"title":false,"claim":true},{"lines":["A vaccine comprising the immunogenic composition of claims 1-12 and a pharmaceutically acceptable excipient."],"number":13,"annotation":false,"title":false,"claim":true},{"lines":["A method of making a vaccine comprising the steps of mixing antigens to make the immunogenic composition of claims 1-12 and adding a pharmaceutically acceptable excipient."],"number":14,"annotation":false,"title":false,"claim":true},{"lines":["A use of the immunogenic composition of claims 1-12 in the manufacture of a vaccine for treatment or prevention of staphylococcal infection."],"number":15,"annotation":false,"title":false,"claim":true}]}},"filters":{"npl":[],"notNpl":[],"applicant":[],"notApplicant":[],"inventor":[],"notInventor":[],"owner":[],"notOwner":[],"tags":[],"dates":[],"types":[],"notTypes":[],"j":[],"notJ":[],"fj":[],"notFj":[],"classIpcr":[],"notClassIpcr":[],"classNat":[],"notClassNat":[],"classCpc":[],"notClassCpc":[],"so":[],"notSo":[],"sat":[]},"sequenceFilters":{"s":"SEQIDNO","d":"ASCENDING","p":0,"n":10,"sp":[],"si":[],"len":[],"t":[],"loc":[]}}