Method And Quantification Assay For Determining C-kit/scf/pakt Status

  • Published: Jan 26, 2011
  • Earliest Priority: Aug 21 2001
  • Family: 21
  • Cited Works: 36
  • Cited by: 0
  • Cites: 4
  • Additional Info: Cited Works Published
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Abstract

The present invention relates to a method for predicting the response to administration of a chemotherapeutic or biological therapeutic agent consisting of tyrosine kinase inhibitors to an individual, comprising detecting the amount of one or a plurality of biological markers in a tissue or cell sample originating from the individual, wherein the biological markers are cellular components to the c-kit pathway and comparing the amount of the one or the plurality of biological markers detected in subpart (a) with the amount detected in one or a plurality of control tissue or cell samples, wherein a response to the administration of a chemotherapeutic or biological therapeutic agent to an individual is predicted based on the comparison of the amount of the one or the plurality of biological markers from one or a plurality of control tissue or cell samples.


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Document History
  • Publication: Jan 26, 2011
  • Application: Aug 21, 2002
    EP EP 10011262 A
  • Priority: Aug 21, 2002
    EP EP 02753517 A
  • Priority: Aug 21, 2001
    US US 31418801 P

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