Oxa1p Enhanced Protein Secretion


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The present invention provides methods and compositions for the efficient and enhanced secretion of a protein of interest from a host cell. In specific, proteins are secreted through the Sec-dependent pathway, involving the spoIIIJ and/or yqjG gene product(s). In some embodiments, expression of the spoIIIJ and/or yqjG gene product(s) is modulated by a promoter operably linked to the gene.


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Document History
  • Publication: Nov 19, 2008
  • Application: Dec 12, 2002
    EP EP 08012307 A
  • Priority: Dec 12, 2002
    EP EP 02790086 A
  • Priority: Nov 15, 2002
    US US 42683202 P
  • Priority: Jan 9, 2002
    US US 34808002 P

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