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(a) a recombinant nucleic acid that encodes a HMG-CoA reductase (HMGR) such that the action of HMGR is increased; and
(b) a genetic modification to increase the supply of acetyl CoA."],"number":1,"annotation":false,"claim":true,"title":false},{"lines":["The microorganism of claim 1 wherein the HMGR is a truncated HMGR in which the regulatory domain has been removed."],"number":2,"annotation":false,"claim":true,"title":false},{"lines":["The microorganism of claim 1 wherein the HMGR copy number is increased."],"number":3,"annotation":false,"claim":true,"title":false},{"lines":["The microorganism of claim 1 which is a fungi."],"number":4,"annotation":false,"claim":true,"title":false},{"lines":["The microorganism of claim 4 wherein said fungi is a yeast."],"number":5,"annotation":false,"claim":true,"title":false},{"lines":["The microorganism of claim 1 wherein said microorganism further comprises a modification to reduce the action of squalene synthase."],"number":6,"annotation":false,"claim":true,"title":false}]}},"filters":{"npl":[],"notNpl":[],"applicant":[],"notApplicant":[],"inventor":[],"notInventor":[],"owner":[],"notOwner":[],"tags":[],"dates":[],"types":[],"notTypes":[],"j":[],"notJ":[],"fj":[],"notFj":[],"classIpcr":[],"notClassIpcr":[],"classNat":[],"notClassNat":[],"classCpc":[],"notClassCpc":[],"so":[],"notSo":[],"sat":[]},"sequenceFilters":{"s":"SEQIDNO","d":"ASCENDING","p":0,"n":10,"sp":[],"si":[],"len":[],"t":[],"loc":[]}}