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Multifunctional Cytokines


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The present invention relates to a novel fusion protein with the formula X-Y, or Y-X, wherein X represents a first immulloregulating polypeptide and Y represents a second immunoregulating polypeptide different from X. The present invention also relates to a nucleic acid molecule encoding such a fusion protein and a vector comprising such a nucleic acid molecule. The present invention also provides infectious viral particles and host cells comprising such a nucleic acid molecule or such a vector as well as a process for producing such infectious viral particles. The present invention also relates to a method for recombinantly producing such a fusion protein. Finally, the present invention also provides a pharmaceutical composition comprising such a fusion protein, a nucleic acid molecule, a vector, infectious viral particles and a host cell as well as the therapeutic use thereof.


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Document History
  • Publication: Jul 16, 2008
  • Application: Jul 20, 2004
    EP EP 08152608 A
  • Priority: Jul 20, 2004
    EP EP 04763359 A
  • Priority: Jul 20, 2004
    EP EP 08152608 A
  • Priority: Jan 28, 2004
    US US 53932004 P
  • Priority: Jul 21, 2003
    EP EP 03360086 A

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