Recombinant Human T2 Rnase And Uses Thereof

  • Published: Jul 11, 2007
  • Earliest Priority: Sep 29 2004
  • Family: 18
  • Cited Works: 0
  • Cited by: 0
  • Cites: 0
  • Sequences: 16
  • Additional Info: Published Sequence
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Abstract

The cloning and heterologous expression of human T2 RNase6PL are disclosed. Further disclosed are methods for preventing, inhibiting and/or reversing cell motility, actin filament assembly or disassembly, proliferation, colonization, differentiation, accumulation and/or development of abnormal cells in a subject is disclosed. The methods are effected by administering to the subject a therapeutically effective amount of a RNase6PL ribonuclease or close homologues thereof.


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Document History
  • Publication: Jul 11, 2007
  • Application: Sep 28, 2005
    EP EP 05789520 A
  • Priority: Sep 28, 2005
    IL IL 2005001041 W
  • Priority: Sep 29, 2004
    US US 61370204 P

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