Insect Chymotrypsin And Inhibitors Thereof

  • Published: Jan 26, 2010
  • Earliest Priority: Apr 23 2003
  • Family: 15
  • Cited Works: 0
  • Cited by: 0
  • Cites: 0
  • Sequences: 93
  • Additional Info: Published Sequence

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The present invention relates generally to a novel chymotrypsin that exhibits resistance to a plant serine proteinase inhibitor. More particularly, the present invention provides a chymotrypsin which is up-regulated in the gut of Helicoverpa armigera and Helicoverpa punctigera insect larvae when fed the serine proteinase inhibitors of Nicotiana alata. The novel chymotrypsin represents, therefore, a target for the identification of antagonists including inhibitors which are proposed to be useful in the control of Helicoverpa spp. populations that have become resistant to serine proteinase inhibitors produced in plants. The antagonists of the chymotrypsin may be topically applied to the plants or, when in proteinaceous form, may be produced by genetic means in plant cells. The antagonists may act at the level of gene expression or protein activity.


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Document History
  • Publication: Jan 26, 2010
  • Application: Apr 23, 2004
    CA CA 2521940 A
  • Priority: Apr 23, 2004
    AU AU 2004/000524 W
  • Priority: Apr 23, 2003
    US US 46505403 P

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