Transgenic Animal Showing Vascular Tissue-specific Expression Of Angiotensin Ii2 Receptor

Abstract

A transgenic animal characterized by showing vascular tissue-specific expression of angiotensin II2 receptor and its descendents; a method for constructing this transgenic animal and its descendents; a recombinant gene for constructing the transgenic animal which contains a promoter region originating in a protein gene expressed in a vascular tissue and an angiotensin II2 receptor gene; a vascular tissue piece or a vascular cell originating in the transgenic animal characterized by showing vascular tissue-specific expression of angiotensin II2 receptor; and a method for analyzing the vascular physiological function and/or blood pressure regulatory function of angiotensin II2 receptor in vitro by using the above-described transgenic animal, vascular tissue or vascular cell.


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Document History
  • Publication: Aug 10, 2000
  • Application: Feb 4, 2000
    WO JP 0000615 W
  • Priority: Feb 5, 1999
    JP 2935499 A

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