The invention relates to the novel materials of formula (I), where: Z is an optionally substituted –O-, -NH, Ncycloalkyl, or Nalkou N-phenyl; n is 0 to 4; R1 is H, Hal, hydroxyl, alkyl, or alkoxy; the alkyl or alkoxy radicals being optionally substituted; R1 can be a phenyl group fused with the phenyl having R1 to form naphthyl; R2 and R3 are H, Hal, or alkyl optionally substituted by one or more halogen atoms; and R4 is H. Said materials can be in any isomeric form and the salts thereof, and are intended for drugs, in particular as AKT(PKB) phosphorylation inhibitors.

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Document History
  • Publication: Jan 6, 2011
  • Application: Jul 1, 2010
    WO FR 2010051376 W
  • Priority: Oct 9, 2009
    FR FR 0957073 A
  • Priority: Sep 10, 2009
    US US 24110109 P
  • Priority: Jul 2, 2009
    FR FR 0903238 A

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