Monoclonal Antibodies Binding To Avian Influenza Virus Subtype H5 Haemagglutinin And Uses Thereof


The present invention provides monoclonal antibodies that specifically bind to the hemagglutinin (HA) of avian influenza virus subtype H5, as well as monoclonal antibodies capable of blocking at least 50% of the HA binding activity of these monoclonal antibodies. Such monoclonal antibodies are useful in the detection, diagnosis, prevention and treatment of avian influenza virus, especially avian influenza virus subtype H5. The present invention also provides hybridoma cell lines, isolated nucleic acid molecules, and short peptides related to the monoclonal antibodies provided herein, and pharmaceutical compositions, medical diagnostic apparatuses and kits containing the monoclonal antibodies provided herein.


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