Means And Methods For Staging, Typing And Treating A Cancerous Disease

  • Published: Aug 2, 2017
  • Earliest Priority: Jan 27 2016
  • Family: 11
  • Cited Works: 93
  • Cited by: 0
  • Cites: 7
  • Sequences: 6
  • Additional Info: Cited Works Sequence
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Abstract

The present invention relates to methods for diagnosing, staging and treating cancer. In particular, the present invention provides methods for determining the stage/type of a cancerous disease, comprising detecting somatic alterations of the DNA of one or more disseminated cancer cells (DCCs), obtained after homing to a distant organ, such as lymph node; and determining the somatic evolution of the DCC(s) based on the detected somatic alterations, wherein the somatic evolution is indicative of the stage/type of the cancerous disease.


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