{"search_session":{},"preferences":{"l":"en","queryLanguage":"en"},"patentId":"189-693-037-099-833","frontPageModel":{"patentViewModel":{"ref":{"entityRefId":"189-693-037-099-833","entityRefType":"PATENT"},"entityMetadata":{"linkedIds":{"empty":true},"tags":[],"collections":[{"id":11720,"type":"PATENT","title":"University of Iowa - Patent Portfolio","description":"","access":"OPEN_ACCESS","displayAvatar":true,"attested":false,"itemCount":3930,"tags":[],"user":{"id":91044780,"username":"Cambialens","firstName":"","lastName":"","created":"2015-05-04T00:55:26.000Z","displayName":"Cambialens","preferences":"{\"usage\":\"public\",\"beta\":false}","accountType":"PERSONAL","isOauthOnly":false},"notes":[{"id":8373,"type":"COLLECTION","user":{"id":91044780,"username":"Cambialens","firstName":"","lastName":"","created":"2015-05-04T00:55:26.000Z","displayName":"Cambialens","preferences":"{\"usage\":\"public\",\"beta\":false}","accountType":"PERSONAL","isOauthOnly":false},"text":"
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This large patent family has been the subject of extensive patent efforts, particularly in the US. The invention relates to the finding that certain unmethylated CpGs activate lymphocytes and simulate the production of IL-12, IFN-? and GM-CSF. The patents in this large family are the key patents for CpG. There are over a hundred patent filings in the family and over 70 of the family members are in the US.
There are numerous granted US patents in this family, including US Patent No. 6,207,646, which claims compositions containing immunostimulatory nucleic acids with consensus mitogenic CpG motifs of certain formulae; US Patent No. 6,239,116 claims methods for inducing Il-6; US Patent No. 6,194,388 claims compositions comprising oligonucleotide sequences which comprise 5’TCAACGTT3’ (where C and G are unmethylated), in combination with an antigen; US Patent No. 7,402,572 claims methods of promoting a Th1 immune response and; US Patent No. 7,674,777 claims immunostimulatory oligonucleotide delivery complexes where the oligonucleotide is covalently linked to the surface of a biodegradable delivery complex.
","published":true,"created":"2010-12-02T04:32:09Z","updated":"2010-12-02T04:32:09Z","sharedType":"PUBLISHED","lensId":"047-161-977-225-100","scope":"FAMILYINFO"}],"inventorships":[],"privateCollections":[],"publicCollections":[{"id":11720,"type":"PATENT","title":"University of Iowa - Patent Portfolio","description":"","access":"OPEN_ACCESS","displayAvatar":true,"attested":false,"itemCount":3930,"tags":[],"user":{"id":91044780,"username":"Cambialens","firstName":"","lastName":"","created":"2015-05-04T00:55:26.000Z","displayName":"Cambialens","preferences":"{\"usage\":\"public\",\"beta\":false}","accountType":"PERSONAL","isOauthOnly":false},"notes":[{"id":8373,"type":"COLLECTION","user":{"id":91044780,"username":"Cambialens","firstName":"","lastName":"","created":"2015-05-04T00:55:26.000Z","displayName":"Cambialens","preferences":"{\"usage\":\"public\",\"beta\":false}","accountType":"PERSONAL","isOauthOnly":false},"text":"Search Applicants and Owners separately: uni* iowa
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Select all patents in the collection and expand by simple families.
Add to collection. Total patents: 3686