Differentiation Of Human Pluripotent Stem Cells

Abstract

The present invention provides a method for increasing the expression of MAFA in cells expressing markers characteristic of the pancreatic endocrine lineage comprising the steps of culturing the cells expressing markers characteristic of the pancreatic endocrine lineage in medium comprising a sufficient amount of a cyclin-dependent kinase inhibitor to cause an increase in expression of MAFA.


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Document History
  • Publication: Sep 5, 2017
  • Application: Dec 9, 2015
    US US 201514963436 A
  • Priority: Dec 9, 2015
    US US 201514963436 A
  • Priority: Oct 23, 2009
    US US 60445709 A
  • Priority: Oct 31, 2008
    US US 11028708 P

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