Backbone Cyclized Inhibitory Peptides Of Myeloid Differentiation Factor 88 (myd88)


The present invention provides backbone cyclized peptides that interfere with signaling of the intracellular adaptor protein My D88. Pharmaceutical compositions comprising these backbone cyclized peptides as well as their use in treatment of multiple sclerosis (MS) and other diseases associated with MyD88 signaling are also disclosed.

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Document History
  • Publication: Dec 14, 2017
  • Application: Jun 4, 2017
    WO IL 2017050621 W
  • Priority: Jun 7, 2016
    US US 201662346580 P

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