Inhibitors Of Notum Pectinacetylesterase And Methods Of Their Use


Compounds are disclosed for the treatment, management and prevention of diseases and disorders affecting the bone. Particular compounds are potent inhibitors of Notum Pectinacetylesterase, and are of the formula: wherein E, G, Y, Z, R1, R2, and R3 are defined herein.

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Document History
  • Publication: Mar 22, 2012
  • Application: Sep 13, 2011
    WO US 2011/0051421 W
  • Priority: Sep 14, 2010
    US US 38252610 P

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