{"search_session":{},"preferences":{"l":"es","queryLanguage":"es"},"patentId":"180-771-468-005-230","frontPageModel":{"patentViewModel":{"ref":{"entityRefType":"PATENT","entityRefId":"180-771-468-005-230"},"entityMetadata":{"linkedIds":{"empty":true},"tags":[],"collections":[{"id":11788,"type":"PATENT","title":"National Tsing Hua University Patent Portfolio","description":"","access":"OPEN_ACCESS","displayAvatar":true,"attested":false,"itemCount":4082,"tags":[],"user":{"id":91044780,"username":"Cambialens","firstName":"","lastName":"","created":"2015-05-04T00:55:26.000Z","displayName":"Cambialens","preferences":"{\"usage\":\"public\",\"beta\":false}","accountType":"PERSONAL","isOauthOnly":false},"notes":[{"id":8421,"type":"COLLECTION","user":{"id":91044780,"username":"Cambialens","firstName":"","lastName":"","created":"2015-05-04T00:55:26.000Z","displayName":"Cambialens","preferences":"{\"usage\":\"public\",\"beta\":false}","accountType":"PERSONAL","isOauthOnly":false},"text":"
Search Applicants and Owners separately:nat* tsing hua uni*. Select more for logical variants. Add to collection. Select all patents in the collection and expand by simple families. Add to collection. Total patents: 3317
Search Applicants and Owners separately:nat* tsing hua uni*. Select more for logical variants. Add to collection. Select all patents in the collection and expand by simple families. Add to collection. Total patents: 3317
a hemagglutinin sequence, being a first nucleotide sequence encoding a first polypeptide, the first polypeptide comprising an amino acid sequence being at least 80% identical to SEQ ID NO:1;\n
a signal peptide sequence, being a second nucleotide sequence encoding a second polypeptide, the second polypeptide comprising a membrane localization sequence; and\n
an incorporation sequence, being a third nucleotide sequence encoding a third polypeptide, the third polypeptide comprising a domain of a viral envelope glycoprotein capable of interacting with a viral nucleocapsid;\n
wherein the HA sequence, the signal peptide sequence, and the incorporation sequence are operably linked to an expression control sequence in an expression vector."],"number":1,"annotation":false,"title":false,"claim":true},{"lines":["The recombinant DNA vector of claim 1, wherein the first polypeptide is at least 95% identical to SEQ ID NO:1."],"number":2,"annotation":false,"title":false,"claim":true},{"lines":["The recombinant DNA vector of claim 1, wherein the first polypeptide is identical to SEQ ID NO:1."],"number":3,"annotation":false,"title":false,"claim":true},{"lines":["The recombinant DNA vector of claim 1, wherein the first nucleic acid sequence is 95% identical to SEQ ID NO:2."],"number":4,"annotation":false,"title":false,"claim":true},{"lines":["The recombinant DNA vector of claim 1, wherein the second nucleotide sequence is operably linked to the 5′-end of the hemagglutinin sequence in the same reading frame, and the second polypeptide comprises the N-terminal signal sequence of the gp64 protein."],"number":5,"annotation":false,"title":false,"claim":true},{"lines":["The recombinant DNA vector of claim 1, wherein the third nucleotide sequence is operably connected to the 3′-end of the hemagglutinin sequence in the same reading frame, and the third polypeptide comprises the C-terminal domain of the gp64 protein."],"number":6,"annotation":false,"title":false,"claim":true},{"lines":["The recombinant DNA vector of claim 1, wherein the third nucleotide sequence is operably connected to the 3′-end of the hemagglutinin sequence in the same reading frame, and the third polypeptide comprises the C-terminal domain of the hemagglutinin protein."],"number":7,"annotation":false,"title":false,"claim":true},{"lines":["The recombinant DNA vector of claim 1, further comprising a fourth nucleotide sequence operably connected to the 5′-end of the hemagglutinin sequence in the same reading frame, the fourth nucleotide sequence encoding a fourth polypeptide, the fourth polypeptide comprising an epitope tag."],"number":8,"annotation":false,"title":false,"claim":true},{"lines":["The recombinant DNA vector of claim 8, wherein the fourth polypeptide comprises 6 histidine residues."],"number":9,"annotation":false,"title":false,"claim":true},{"lines":["The recombinant DNA vector of claim 1 wherein the expression vector is a baculovirus vector."],"number":10,"annotation":false,"title":false,"claim":true},{"lines":["The recombinant DNA vector of claim 1, wherein the expression vector is a baculovirus vector derived from the pFastBac™ DUAL vector."],"number":11,"annotation":false,"title":false,"claim":true},{"lines":["The recombinant DNA vector of claim 1, wherein the expression control sequence is a p10 promoter."],"number":12,"annotation":false,"title":false,"claim":true},{"lines":["The recombinant DNA vector of claim 1, wherein the expression control sequence is a polyhedrin promoter."],"number":13,"annotation":false,"title":false,"claim":true},{"lines":["A method for displaying an avian influenza antigen on a cell membrane of a host cell of a host or viral envelope of a virus, comprising:\n
introducing the recombinant DNA vector of claim 1 into the host."],"number":14,"annotation":false,"title":false,"claim":true},{"lines":["The recombinant DNA vector of claim 14, wherein the avian influenza antigen is hemagglutinin."],"number":15,"annotation":false,"title":false,"claim":true},{"lines":["The recombinant DNA vector of claim 14, wherein the virus is a baculovirus."],"number":16,"annotation":false,"title":false,"claim":true},{"lines":["A method for inducing immunogenicity in a host comprising:\n
introducing the recombinant DNA vector of claim 1 into the host."],"number":17,"annotation":false,"title":false,"claim":true},{"lines":["A method for increasing the titer of antibodies against an avian influenza antigen in a host, comprising:\n
introducing the recombinant DNA vector of claim 1 into the host."],"number":18,"annotation":false,"title":false,"claim":true},{"lines":["The method of claim 18, wherein the avian influenza antigen comprises hemagglutinin."],"number":19,"annotation":false,"title":false,"claim":true}]}},"filters":{"npl":[],"notNpl":[],"applicant":[],"notApplicant":[],"inventor":[],"notInventor":[],"owner":[],"notOwner":[],"tags":[],"dates":[],"types":[],"notTypes":[],"j":[],"notJ":[],"fj":[],"notFj":[],"classIpcr":[],"notClassIpcr":[],"classNat":[],"notClassNat":[],"classCpc":[],"notClassCpc":[],"so":[],"notSo":[],"sat":[]},"sequenceFilters":{"s":"SEQIDNO","d":"ASCENDING","p":0,"n":10,"sp":[],"si":[],"len":[],"t":[],"loc":[]}}