Cdnas And Proteins Involved In Hypoxia, Circadian And Orphan Signal Transduction Pathways, And Methods Of Use


The present invention provides isolated nucleic acids and proteins that are new and distinct members of the bHLH-PAS superfamily of transcription regulators. These "MOPs" (members of PAS) are useful in a variety of research, diagnostic and therapeutic applications. Several of the MOPs of the present invention are alpha-class hypoxia-inducible factors. Several other of the MOPs of the invention are involved in circadian signal transduction.

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Document History
  • Publication: Mar 10, 2009
  • Application: Nov 29, 2005
    US US 28872005 A
  • Priority: Nov 29, 2005
    US US 28872005 A
  • Priority: Jul 24, 2000
    US US 55536200 A
  • Priority: Nov 27, 1998
    US US 9825314 W
  • Priority: Nov 28, 1997
    US US 6686397 P

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