Magnetic Resonance Imaging Of Ventilation And Perfusion In The Lung

Abstract

Methods, devices, and systems are disclosed for implementing a fully quantitative non-injectable contrast proton MRI technique to measure spatial ventilation-perfusion (VA/Q) matching and spatial distribution of ventilation and perfusion. In one aspect, a method using MRI to characterize ventilation and perfusion in a lung includes acquiring an MR image of the lung having MR data in a voxel and obtaining a breathing frequency parameter, determining a water density value, a specific ventilation value, and a perfusion value in at least one voxel of the MR image based on the MR data and using the water density value to determine an air content value, and determining a ventilation-perfusion ratio value that is the product of the specific ventilation value, the air content value, the inverse of the perfusion value, and the breathing frequency.


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Document History
  • Publication: Sep 5, 2017
  • Application: Dec 7, 2011
    US US 201113992231 A
  • Priority: Dec 7, 2011
    US US 201113992231 A
  • Priority: Dec 7, 2011
    US US 2011/0063854 W
  • Priority: Dec 7, 2010
    US US 42055410 P

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