Dry Powders Of Cannabinoids And Methods For Preparing Dry Powders

  • Published: Sep 27, 2018
  • Earliest Priority: Mar 22 2017
  • Family: 6
  • Cited Works: 45
  • Cited by: 1
  • Cites: 4
  • Additional Info: Cited Works Full text
Abstract

Dry powders comprise a cannabinoid, a polymer binding agent, a dispersing agent, and a bulking agent, and optionally an antioxidant, and are formed by carbon dioxide-assisted nebulization and drying in a flowing dry stream of gas. The dry powders have an aerodynamic particle distribution effective for delivery by respiration into the lungs of a patient. Methods of preparing a dry powder comprise subjecting a solution of a volatile component, a cannabinoid, a polymer binding agent, a dispersing agent, and a bulking agent, and optionally an antioxidant, to carbon dioxide-assisted nebulization, and drying droplets formed by the nebulization in a flowing dry gas stream to form a dry powder. The dry powder has an aerodynamic particle distribution effective for delivery of the dry powder by respiration into a lung of a patient and/or exhibit increased bioavailability and/or storage stability of a cannabinoid. The dry powder can be compressed into a wafer.


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Document History
  • Publication: Sep 27, 2018
  • Application: Mar 21, 2018
    WO US 2018/0023633 W
  • Priority: Mar 22, 2017
    US US 201715466719 A

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