{"search_session":{},"preferences":{"l":"en","queryLanguage":"en"},"patentId":"174-225-335-789-099","frontPageModel":{"patentViewModel":{"ref":{"entityRefType":"PATENT","entityRefId":"174-225-335-789-099"},"entityMetadata":{"linkedIds":{"empty":true},"tags":[],"collections":[{"id":8876,"type":"PATENT","title":"Northwestern University Patent Portfolio","description":"","access":"OPEN_ACCESS","displayAvatar":true,"attested":false,"itemCount":17491,"tags":[],"user":{"id":91044780,"username":"Cambialens","firstName":"","lastName":"","created":"2015-05-04T00:55:26.000Z","displayName":"Cambialens","preferences":"{\"usage\":\"public\",\"beta\":false}","accountType":"PERSONAL","isOauthOnly":false},"notes":[{"id":8210,"type":"COLLECTION","user":{"id":91044780,"username":"Cambialens","firstName":"","lastName":"","created":"2015-05-04T00:55:26.000Z","displayName":"Cambialens","preferences":"{\"usage\":\"public\",\"beta\":false}","accountType":"PERSONAL","isOauthOnly":false},"text":"
Search applicants and Owners separately = \" Northwestern University\", 'Northw* Univ*\" , \"Univ Northwestern\", \"
Search applicants and Owners separately = \" Northwestern University\", 'Northw* Univ*\" , \"Univ Northwestern\", \"
obtaining heart rate data from the patient before an operation, the data being obtained in a preoperative time period including a nocturnal time period and a diurnal time period;\n
carrying out a dynamic heart rate variability analysis of nocturnal heart rate data and of diurnal heart rate data to obtain a short term fractal correlation property of heart rate variability in a defined nocturnal time period and in a defined diurnal time period;\n
comparing the defined nocturnal time period short term fractal correlation property and the defined diurnal time period short term fractal correlation property;\n
determining from the comparison whether the nocturnal time period short term fractal correlation property is less than the diurnal time period short term fractal correlation property; and\n
establishing a determination that the defined nocturnal time period short term fractal correlation property is less than the defined diurnal time period short term fractal correlation property as predictive for myocardial ischemia in a time subsequent to obtaining the heart rate data from the patient."],"number":1,"annotation":false,"title":false,"claim":true},{"lines":["The method of claim 1 wherein the heart rate variability analysis is detrended fluctuation analysis (DFA)."],"number":2,"annotation":false,"title":false,"claim":true},{"lines":["The method of claim 2 wherein a scaling exponent α1 of the DFA is used as a short-term fractal correlation property."],"number":3,"annotation":false,"title":false,"claim":true},{"lines":["The method of claim 1 or 2 wherein the analysis is on-line analysis."],"number":4,"annotation":false,"title":false,"claim":true},{"lines":["The method of claim 2 wherein the heart rate data obtaining is initiated at least a day before the operation."],"number":5,"annotation":false,"title":false,"claim":true},{"lines":["The method of claim 5 wherein the heart rate data obtained is ECG data obtained using Holter recording."],"number":6,"annotation":false,"title":false,"claim":true},{"lines":["The method of claim 1 wherein the heart rate data obtaining is initiated at least a day before the operation."],"number":7,"annotation":false,"title":false,"claim":true},{"lines":["The method of claim 7 wherein the heart rate data obtained is ECG data obtained using Holter recording."],"number":8,"annotation":false,"title":false,"claim":true},{"lines":["A method for predicting perioperative myocardial ischemia in a patient, the method comprising the steps of:\n
obtaining heart rate data perioperatively from the patient in a time period including a defined recent data acquisition time period and a defined data acquisition time period earlier than, and preceding, the defined recent data acquisition time period;\n
carrying out a dynamic heart rate variability analysis of heart rate data from the recent time period and of heart rate data from the earlier time period to obtain a short term fractal correlation property of heart rate variability in a defined recent data acquisition time period and in a defined earlier data acquisition time period;\n
comparing the defined recent data acquisition time period short term fractal correlation property and the defined earlier data acquisition time period short term fractal correlation property;\n
determining from the comparison whether the recent data acquisition time period short term fractal correlation property is less than the earlier data acquisition time period short term fractal correlation property; and\n
establishing a determination that the defined recent data acquisition time period short term fractal correlation property is less than the defined earlier data acquisition time period short term fractal correlation as predictive for myocardial ischemia in a time subsequent to obtaining the heart rate data from the patient."],"number":9,"annotation":false,"title":false,"claim":true},{"lines":["The method of claim 9 wherein the heart rate variability analysis is detrended fluctuation analysis (DFA)."],"number":10,"annotation":false,"title":false,"claim":true},{"lines":["The method of claim 10 wherein a scaling exponent α1 of the DFA is used as a short-term fractal correlation property."],"number":11,"annotation":false,"title":false,"claim":true},{"lines":["The method of claim 9 or 10 wherein the analysis is on-line analysis."],"number":12,"annotation":false,"title":false,"claim":true},{"lines":["The method of claim 10 wherein the heart rate analysis of the acquired heart rate data is performed perioperatively."],"number":13,"annotation":false,"title":false,"claim":true},{"lines":["The method of claim 13 wherein the heart rate data obtained is ECG data obtained using Holter recording."],"number":14,"annotation":false,"title":false,"claim":true},{"lines":["The method of claim 9 wherein the heart rate analysis of the acquired heart rate data is performed perioperatively."],"number":15,"annotation":false,"title":false,"claim":true},{"lines":["The method of claim 15 wherein the heart rate data obtained is ECG data obtained using Holter recording."],"number":16,"annotation":false,"title":false,"claim":true},{"lines":["The method of claim 9 wherein the time periods used for comparison include at least two of; a recent data acquisition time period from 30–0 minutes prior to a recent point in time; an earlier data acquisition time period 60–30 minutes prior to the recent point in time; and an earlier 24 hour data acquisition time period."],"number":17,"annotation":false,"title":false,"claim":true},{"lines":["An arrangement for predicting perioperative myocardial ischemia in a patient, the arrangement comprising:\n
means for obtaining heart rate data from the patient before an operation, the data being obtained in a preoperative time period including a nocturnal time period and a diurnal time period;\n
means receiving the obtained heart rate data for carrying out a dynamic heart rate variability analysis of nocturnal heart rate data and of diurnal heart rate data to obtain a short term fractal correlation property of heart rate variability in a defined nocturnal time period and in a defined diurnal time period;\n
means for comparing the defined nocturnal time period short term fractal correlation property and the defined diurnal time period short term fractal correlation property to determine from the comparison whether the nocturnal time period short term fractal correlation property is less than the diurnal time period short term fractal correlation property, and for establishing a determination that the nocturnal time period short term fractal correlation property is less than the diurnal time period short term fractal correlation property as a predictor for myocardial ischemia in a time subseciuent to obtaining the heart rate data from the patient."],"number":18,"annotation":false,"title":false,"claim":true},{"lines":["The arrangement of claim 18 wherein the short term fractal analysis property is obtained from detrended fluctuation analysis (DFA)."],"number":19,"annotation":false,"title":false,"claim":true},{"lines":["The arrangement of claim 19 wherein a scaling exponent α1 of the DFA is used as a short-term fractal correlation property."],"number":20,"annotation":false,"title":false,"claim":true},{"lines":["The arrangement of claim 18 or 19 wherein said means for carrying out dynamic heart rate variability analysis carries out on-line analysis."],"number":21,"annotation":false,"title":false,"claim":true},{"lines":["The arrangement of claim 19 wherein said obtaining means initiates the heart rate data obtaining at least a day before the operation."],"number":22,"annotation":false,"title":false,"claim":true},{"lines":["The arrangement of claim 22 wherein the heart rate data obtaining means is a Holter recorder obtaining ECG data."],"number":23,"annotation":false,"title":false,"claim":true},{"lines":["The arrangement of claim 18 wherein said obtaining means initiates the heart rate data obtaining at least a day before the operation."],"number":24,"annotation":false,"title":false,"claim":true},{"lines":["The arrangement of claim 24 wherein the heart rate data obtaining means is a Holter recorder for obtaining ECG data."],"number":25,"annotation":false,"title":false,"claim":true},{"lines":["An arrangement for predicting perioperative myocardial ischemia in a patient, the arrangement comprising:\n
means for obtaining heart rate data perioperatively from the patient in a time period including a defined recent data acquisition time period and a defined data acquisition time period earlier than, and preceding, the recent data acquisition time period;\n
means receiving the obtained heart rate data for carrying out a dynamic heart rate variability analysis of heart rate data from the recent time period and heart rate data from the earlier data acquisition time period to obtain a short term fractal correlation property of heart rate variability in a defined recent data acquisition time period and in a defined earlier time period;\n
means for comparing the defined recent data acquisition time period short term fractal correlation property and the defined earlier data acquisition time period short term fractal correlation property to determine from the comparison whether the recent data acquisition time period short term fractal correlation property is less than the earlier data acquisition time period short term fractal correlation property, and for establishing a determination that the defined recent data acquisition time period short term fractal correlation property is less than the defined earlier data acquisition time period short term fractal correlation as a predictor for myocardial ischemia in a time subsequent to obtaining the heart rate data from the patient."],"number":26,"annotation":false,"title":false,"claim":true},{"lines":["The arrangement of claim 26 wherein the short term fractal analysis property is obtained from detrended fluctuation analysis (DFA)."],"number":27,"annotation":false,"title":false,"claim":true},{"lines":["The arrangement of claim 27 wherein a scaling exponent α1 of the DFA is used as a short-term fractal correlation property."],"number":28,"annotation":false,"title":false,"claim":true},{"lines":["The arrangement of claim 27 wherein said means for carrying out dynamic heart rate variability analysis carries out the analysis perioperatively."],"number":29,"annotation":false,"title":false,"claim":true},{"lines":["The arrangement of claim 29 wherein the heart rate data obtaining means is a Holter recorder obtaining ECG data."],"number":30,"annotation":false,"title":false,"claim":true},{"lines":["The arrangement of claim 26 wherein said means for carrying out dynamic heart rate variability analysis carries out the analysis perioperatively."],"number":31,"annotation":false,"title":false,"claim":true},{"lines":["The arrangement of claim 31 wherein the heart rate data obtaining means is a Holter recorder for obtaining ECG data."],"number":32,"annotation":false,"title":false,"claim":true},{"lines":["The arrangement of claim 26 wherein said means for carrying out dynamic heart rate variability analysis carries out on-line analysis."],"number":33,"annotation":false,"title":false,"claim":true},{"lines":["The arrangement of claim 26 wherein said comparing means uses at least two of; a recent data acquisition time period from 30–0 minutes prior to the recent point in time; an earlier data acquisition time period 60–30 minutes prior to the recent point in time; and an earlier 24 hour data acquisition time period."],"number":34,"annotation":false,"title":false,"claim":true}]}},"filters":{"npl":[],"notNpl":[],"applicant":[],"notApplicant":[],"inventor":[],"notInventor":[],"owner":[],"notOwner":[],"tags":[],"dates":[],"types":[],"notTypes":[],"j":[],"notJ":[],"fj":[],"notFj":[],"classIpcr":[],"notClassIpcr":[],"classNat":[],"notClassNat":[],"classCpc":[],"notClassCpc":[],"so":[],"notSo":[],"sat":[]},"sequenceFilters":{"s":"SEQIDNO","d":"ASCENDING","p":0,"n":10,"sp":[],"si":[],"len":[],"t":[],"loc":[]}}