Methods And Kits For Treating And Classifying Individuals At Risk Of Or Suffering From Trap1 Change-of-function

Abstract

The present disclosure provides methods and kits for treating and classifying individuals at risk of or suffering from a neurological and/or mitochondrial dysfunction or disorder. In general, the individuals are treated and/or classified based on the presence of a change-of-function mutation in nuclear DNA that encodes TNF receptor-associated protein 1 (TRAP1). Treatment involves the administration of a therapeutically effective amount of an antioxidant.


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Document History
  • Publication: Jun 6, 2017
  • Application: Jun 11, 2014
    US US 201414895557 A
  • Priority: Jun 11, 2014
    US US 201414895557 A
  • Priority: Jun 11, 2014
    US US 2014/0041969 W
  • Priority: Jun 11, 2013
    US US 201361833596 P

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