Cdna Clone-launched Platform For High-yield Production Of Inactivated Zika Virus

Abstract

The invention generally relates to the development of variant Zika strains, cDNA clones and mRNA transcripts that contain specific mutations in the Zika ORF, and methods for producing high yields of Zika viruses (“ZIKVs”) using these variant cDNA clones, transcripts and strains. The produced ZIKVs can be used for the manufacture of purified inactivated vaccines (PIVs), which may be useful for treating ZIKV-related diseases and for providing immunoprotection against ZIKV.


Claims
CPC Classifications
Download PDF
Document Preview
Document History
  • Publication: Mar 26, 2019
  • Application: Feb 15, 2018
    US US 201815897488 A
  • Priority: Feb 15, 2018
    US US 201815897488 A
  • Priority: Feb 15, 2017
    US US 201762459367 P

Download Citation


Sign in to the Lens

Feedback