Modulation Of Synaptic Maintenance

Abstract

C1q is shown to be expressed in neurons, where it acts as a signal for synapse elimination. Methods are provided for protecting or treating an individual suffering from adverse effects of synapse loss. These findings have broad implications for a variety of clinical conditions, including Alzheimer's disease.


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Document History
  • Publication: Jul 5, 2016
  • Application: Jun 26, 2015
    US US 201514751921 A
  • Priority: Jun 26, 2015
    US US 201514751921 A
  • Priority: Dec 14, 2011
    US US 201113326180 A
  • Priority: Dec 8, 2006
    US US 63600106 A
  • Priority: Dec 9, 2005
    US US 74907105 P

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