Water Soluble Reactive Derivatives Of Carboxy Polysaccharides And Fibrinogen Conjugates Thereof

  • Published: Jul 10, 2008
  • Earliest Priority: Jan 04 2007
  • Family: 6
  • Cited Works: 0
  • Cited by: 8
  • Cites: 1
  • Additional Info: Full text Published

The present invention provides water-soluble reactive esters of carboxy polysaccharides and derivatives thereof. The reactive carboxy polysaccharide derivatives are useful per se in aqueous solutions or specifically for the formation of water-soluble covalent fibrinogen conjugates. A preferred conjugate is a hyaluronic acid-fibrinogen conjugate and fibrin adhesive, clot or matrix derived from it. Methods of preparation and methods of use in tissue repair and regeneration are disclosed.

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Document History
  • Publication: Jul 10, 2008
  • Application: Jan 6, 2008
    WO IL 2008000033 W
  • Priority: Jan 4, 2007
    US US 87839107 P

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