Substituted Heteroarylpiperidine Derivatives As Melanocortin-4 Receptor Modulators

  • Published: Jul 28, 2010
  • Earliest Priority: Jan 14 2009
  • Family: 2
  • Cited Works: 24
  • Cited by: 0
  • Cites: 7
  • Additional Info: Cited Works Published

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The present invention relates to substituted heteroarylpiperidine derivatives as melanocortin-4 receptor modulators, in particular as melanocortin 4 receptor antagonists. The antagonists are useful for the treatment of disorders and diseases such as cachexia induced by e.g. cancer, chronic kidney disease (CKD) or chronic heart failure (CHF), muscle wasting, anorexia induced by e.g. chemotherapy or radiotherapy, anorexia nervosa, amyotrophic lateral sclerosis (ALS), pain, neuropathic pain, anxiety and depression, nausea and emesis.


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Document History
  • Publication: Jul 28, 2010
  • Application: Jan 14, 2009
    EP EP 09000437 A
  • Priority: Jan 14, 2009
    EP EP 09000437 A

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