Means And Methods For The Production Of Amyloid Oligomers

Abstract

The present invention relates to the field of amyloid disorders, more particularly to the field of diseases where protein misfolding leads to the generation of insoluble amyloid fibers in tissues and organs. The invention provides methods for the production of soluble, toxic amyloid oligomers. The invention further provides assays using said amyloid oligomers to screen for molecules that interfere with the toxicity of said oligomers.


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Document History
  • Publication: Mar 13, 2008
  • Application: Sep 6, 2007
    WO EP 2007059327 W
  • Priority: May 4, 2007
    US US 92768107 P
  • Priority: Sep 8, 2006
    EP EP 06120346 A
  • Priority: Sep 8, 2006
    US US 84307606 P

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