Modulation Of Apolipoprotein Ciii (apociii) Expression

Abstract

Provided herein are methods, compounds, and compositions for reducing expression of ApoCIII mRNA and protein in an animal. Also provided herein are methods, compounds, and compositions for increasing HDL levels and/or improving the ratio of TG to HDL and reducing plasma lipids and plasma glucose in an animal. Such methods, compounds, and compositions are useful to treat, prevent, delay, or ameliorate any one or more of cardiovascular disease or metabolic disorder, or a symptom thereof.


Claims
Download PDF
Document Preview
Document History
  • Publication: Oct 13, 2015
  • Application: Apr 27, 2012
    US US 201214114187 A
  • Priority: Apr 27, 2012
    US US 201214114187 A
  • Priority: Apr 27, 2012
    US US 2012/0035694 W
  • Priority: Feb 3, 2012
    US US 201261595009 P
  • Priority: Apr 27, 2011
    US US 201161479817 P

Download Citation


Sign in to the Lens

Feedback