Method For Inducing Antitumor Immunity Using Sindbis Viral Vectors And Tumor Associated Antigens

Abstract

The subject application is directed to a method for treating a mammal harboring a tumor comprising identifying a tumor associated antigen (TAA) expressed by the tumor and parenterally administering to the mammal a therapeutically effective amount of a Sindbis viral vector carrying a gene encoding the TAA to the mammal sufficient to elicit an immune response directed against the tumor, and thereby treating the tumor.


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Document History
  • Publication: Jul 3, 2018
  • Application: Sep 5, 2014
    US US 201414478783 A
  • Priority: Sep 5, 2014
    US US 201414478783 A
  • Priority: Sep 6, 2013
    US US 201361874685 P

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