G Proteins In Tumor Growth And Angiogenesis

Abstract

The invention provides an agent that reduces the expression of Gα12 or Gα13 polypeptide, as well as an agent that enhances G protein Gα12 or Gα13 expression and/or activity. An agent of the invention may be used to decrease or increase G protein Gα12 or Gα13 expression and/or activity thereby to treat or prevent the onset of a disease or condition associated with Gα12 or Gα13 expression and/or activity. The invention also provides a method for screening for an anti-cancer or anti-angiogenesis agent, as well as an agent that promotes angiogenesis.


Claims
Download PDF
Document Preview
Document History
  • Publication: Feb 26, 2013
  • Application: May 24, 2007
    US US 80571507 A
  • Priority: May 24, 2007
    US US 80571507 A
  • Priority: May 25, 2006
    US US 80848906 P

Download Citation


Sign in to the Lens

Feedback