Sirt1 Modulators For Manipulating Cell/organism Lifespan/stress Response

Full-text?

The full document isn't yet available to us from the patent office.

Abstract

Provided herein are methods and compositions for modulating the activity of sirtuin deacetylase protein family members; p53 activity; apoptosis; lifespan and sensitivity to stress of cells and organisms. Exemplary methods comprise contacting a cell with an activating compound, such as a flavone, stilbene, flavanone, isoflavone, catechin, chalcone, tannin or anthocyanidin; or an inhibitory compound, such as a sphingolipid, e.g., sphingosine.


Claims

Information currently unavailable.

Download Citation


Sign in to the Lens

Feedback