Generation Of Induced Pluripotent Stem Cells From Small Volumes Of Peripheral Blood

Abstract

Methods and compositions relating to the production of induced pluripotent stem cells (iPS cells) are disclosed. For example, induced pluripotent stem cells may be generated from peripheral blood cells, such as human blood progenitor cells, using episomal reprogramming and feeder-free or xeno-free conditions. In certain embodiments, the invention provides novel methods for improving overall reprogramming efficiency with low number of blood progenitor cells.


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Document History
  • Publication: Dec 22, 2011
  • Application: Jun 14, 2011
    WO US 2011/0040323 W
  • Priority: Oct 1, 2010
    US US 38894910 P
  • Priority: Jun 15, 2010
    US US 35504610 P

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