{"search_session":{},"preferences":{"l":"en","queryLanguage":"en"},"patentId":"158-244-236-173-09X","frontPageModel":{"patentViewModel":{"ref":{"entityRefType":"PATENT","entityRefId":"158-244-236-173-09X"},"entityMetadata":{"linkedIds":{"empty":true},"tags":[],"collections":[{"id":8759,"type":"PATENT","title":"University of Columbia","description":"","access":"OPEN_ACCESS","displayAvatar":true,"attested":false,"itemCount":13487,"tags":[],"user":{"id":91044780,"username":"Cambialens","firstName":"","lastName":"","created":"2015-05-04T00:55:26.000Z","displayName":"Cambialens","preferences":"{\"usage\":\"public\",\"beta\":false}","accountType":"PERSONAL","isOauthOnly":false},"notes":[{"id":8203,"type":"COLLECTION","user":{"id":91044780,"username":"Cambialens","firstName":"","lastName":"","created":"2015-05-04T00:55:26.000Z","displayName":"Cambialens","preferences":"{\"usage\":\"public\",\"beta\":false}","accountType":"PERSONAL","isOauthOnly":false},"text":"
Searched applicants and Owners= \"Columbia Univ\", \"Univ Columbia\", \" Univ Colum*\", \"Colum* univ\", \"Univ* Colum* NOT British\".
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Searched applicants and Owners= \"Columbia Univ\", \"Univ Columbia\", \" Univ Colum*\", \"Colum* univ\", \"Univ* Colum* NOT British\".
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Total patents: more than 10k
a) culturing the embryonic stem cell in a composition essentially free of any retinoid and comprising Advanced Dulbecco's Modified Eagle's Medium/F12 and Neurobasal medium that has been supplemented with 10% Knockout-Serum Replacement (ADFNK medium) wherein the amount of the composition is effective to generate the caudal brachial motor neuron under conditions such that the caudal brachial motor neuron is produced, and\n
b) recovering the caudal brachial motor neuron so produced."],"number":1,"annotation":false,"title":false,"claim":true},{"lines":["The method of claim 1, wherein during culturing the embryonic stem cell is contacted with at least one neurotrophic factor."],"number":2,"annotation":false,"title":false,"claim":true},{"lines":["The method of claim 1, wherein the embryonic stem cell is a murine embryonic stem cell."],"number":3,"annotation":false,"title":false,"claim":true},{"lines":["The method of claim 1, wherein the embryonic stem cell is a human embryonic stem cell."],"number":4,"annotation":false,"title":false,"claim":true},{"lines":["The method of claim 1, wherein the caudal brachial motor neuron is transfected so that it expresses enhanced green fluorescent protein (eGFP)."],"number":5,"annotation":false,"title":false,"claim":true},{"lines":["The method of claim 1, wherein the culturing is effected in vivo in a subject."],"number":6,"annotation":false,"title":false,"claim":true},{"lines":["The method of claim 1, wherein the culturing is effected in vitro."],"number":7,"annotation":false,"title":false,"claim":true},{"lines":["A method for producing a caudal motor neuron comprising\n
a) culturing an embryonic stem cell in a serum-free neural induction composition which is essentially free of any retinoid and comprises an isotonic salt solution, wherein the amount of the composition is effective to generate the caudal motor neuron under condition such that the caudal motor neuron is produced, and\n
b) recovering the caudal motor neuron so produced."],"number":8,"annotation":false,"title":false,"claim":true},{"lines":["The method of claim 8, wherein during culturing the embryonic stem cell is contacted with at least one neurotrophic factor."],"number":9,"annotation":false,"title":false,"claim":true},{"lines":["The method of claim 8, wherein the embryonic stem cell is a murine embryonic stem cell."],"number":10,"annotation":false,"title":false,"claim":true},{"lines":["The method of claim 8, wherein the embryonic stem cell is a human embryonic stem cell."],"number":11,"annotation":false,"title":false,"claim":true},{"lines":["The method of claim 8, wherein the caudal motor neuron is transfected so that it expresses enhanced green fluorescent protein (eGFP)."],"number":12,"annotation":false,"title":false,"claim":true},{"lines":["The method of claim 8, wherein the culturing is effected in vivo in a subject."],"number":13,"annotation":false,"title":false,"claim":true},{"lines":["The method of claim 8, wherein the culturing is effected in vitro."],"number":14,"annotation":false,"title":false,"claim":true},{"lines":["The method of claim 8, wherein composition further comprises an amount of Fibroblast Growth Factor-2 (FGF-2)."],"number":15,"annotation":false,"title":false,"claim":true},{"lines":["The method of claim 8, wherein composition further comprises an amount of Growth differentiation factor 11 (Gdf11)."],"number":16,"annotation":false,"title":false,"claim":true},{"lines":["The method of claim 8, wherein composition further comprises an amount of a Wnt factor."],"number":17,"annotation":false,"title":false,"claim":true},{"lines":["The method of claim 8, wherein composition further comprises an amount of Fibroblast Growth Factor-2 (FGF-2), an amount of Growth differentiation factor 11 (Gdf11), and an amount of a Wnt factor."],"number":18,"annotation":false,"title":false,"claim":true}]}},"filters":{"npl":[],"notNpl":[],"applicant":[],"notApplicant":[],"inventor":[],"notInventor":[],"owner":[],"notOwner":[],"tags":[],"dates":[],"types":[],"notTypes":[],"j":[],"notJ":[],"fj":[],"notFj":[],"classIpcr":[],"notClassIpcr":[],"classNat":[],"notClassNat":[],"classCpc":[],"notClassCpc":[],"so":[],"notSo":[],"sat":[]},"sequenceFilters":{"s":"SEQIDNO","d":"ASCENDING","p":0,"n":10,"sp":[],"si":[],"len":[],"t":[],"loc":[]}}