Topical, Periocular, Or Intraocular Use Of Tocotrienols For The Treatment Of Ophthalmic Diseases


A method for preventing, reducing, ameliorating or treating ophthalmic disorders associated with neurodegenerative diseases or trauma, comprising the topical, periocular, or intraocular application of an ophthalmic formulation comprising a therapeutically effective amount of one or more ophthalmic agents selected from the group consisting of alpha-tocotrienol, beta-tocotrienol, gamma-tocotrienol, delta-tocotrienol, or esters or mixtures thereof is disclosed. Use of tocotrienols for the prevention, reduction, amelioration or treatment of ophthalmic disorders that are, or that are associated with, mitochondrial diseases is also discussed. Topical ophthalmic formulations comprising tocotrienols are also discussed.

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Document History
  • Publication: May 31, 2012
  • Application: Apr 27, 2010
    US US 201013266240 A
  • Priority: Apr 27, 2010
    US US 2010/0032622 W
  • Priority: Apr 27, 2010
    US US 201013266240 A
  • Priority: Apr 28, 2009
    US US 21476009 P

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