{"search_session":{},"preferences":{"l":"en","queryLanguage":"en"},"patentId":"153-382-820-805-205","frontPageModel":{"patentViewModel":{"ref":{"entityRefType":"PATENT","entityRefId":"153-382-820-805-205"},"entityMetadata":{"linkedIds":{"empty":true},"tags":[],"collections":[{"id":11855,"type":"PATENT","title":"University of Montpellier Patent Portfolio","description":"","access":"OPEN_ACCESS","displayAvatar":true,"attested":false,"itemCount":11808,"tags":[],"user":{"id":91044780,"username":"Cambialens","firstName":"","lastName":"","created":"2015-05-04T00:55:26.000Z","displayName":"Cambialens","preferences":"{\"usage\":\"public\",\"beta\":false}","accountType":"PERSONAL","isOauthOnly":false},"notes":[{"id":8467,"type":"COLLECTION","user":{"id":91044780,"username":"Cambialens","firstName":"","lastName":"","created":"2015-05-04T00:55:26.000Z","displayName":"Cambialens","preferences":"{\"usage\":\"public\",\"beta\":false}","accountType":"PERSONAL","isOauthOnly":false},"text":"
Search Applicants and Owners separately:univ* AND Montpellier. Select more for logical variants. Add to collection. Select all patents in the collection and expand by simple families. Add to collection. Total patents: 1289
Search Applicants and Owners separately:univ* AND Montpellier. Select more for logical variants. Add to collection. Select all patents in the collection and expand by simple families. Add to collection. Total patents: 1289
a) a yeast vehicle; and\n
b) an HCV NS3-Core fusion protein comprising HCV sequences, wherein the HCV sequences consist of:\n\n(1) an HCV NS3 protease sequence consisting of the 262 amino acids of HCV NS3 protease following the initial N-terminal 88 amino acids of full-length HCV NS3 protease (positions 1115 to 1376 with respect to SEQ ID NO:20); and\n(2) an HCV Core sequence consisting of amino acid positions 2 through 140 of full-length HCV Core sequence (positions 2 to 140, with respect to SEQ ID NO:20);\n
wherein the HCV fusion protein is expressed by the yeast vehicle; and\n
wherein the composition elicits an HCV NS3-specific immune response and an HCV Core-specific immune response."],"number":1,"annotation":false,"title":false,"claim":true},{"lines":["The composition of claim 1, wherein the HCV Core sequence has been appended to include glutamate and aspartate."],"number":2,"annotation":false,"title":false,"claim":true},{"lines":["The composition of claim 1, wherein the HCV Core sequence has been appended to include the amino acid sequence of SEQ ID NO: 10."],"number":3,"annotation":false,"title":false,"claim":true},{"lines":["The composition of claim 1, wherein the HCV NS3 protease sequence is linked at its N-terminus to the amino acid sequence represented by SEQ ID NO:9."],"number":4,"annotation":false,"title":false,"claim":true},{"lines":["The composition of claim 1, wherein the composition further comprises a dendritic cell, wherein the dendritic cell has been loaded intracellularly with the yeast vehicle and the HCV fusion protein."],"number":5,"annotation":false,"title":false,"claim":true},{"lines":["The composition of claim 1, wherein the expression of the fusion protein is under the control of an inducible promoter."],"number":6,"annotation":false,"title":false,"claim":true},{"lines":["The composition of claim 1, further comprising at least one biological response modifier."],"number":7,"annotation":false,"title":false,"claim":true},{"lines":["The composition of claim 1, wherein the composition is formulated for injection."],"number":8,"annotation":false,"title":false,"claim":true},{"lines":["The composition of claim 1, wherein the yeast vehicle is a whole yeast."],"number":9,"annotation":false,"title":false,"claim":true},{"lines":["The composition of claim 9, wherein the whole yeast is killed."],"number":10,"annotation":false,"title":false,"claim":true},{"lines":["The composition of claim 9, wherein the whole yeast is heat-inactivated."],"number":11,"annotation":false,"title":false,"claim":true},{"lines":["The composition of claim 11, wherein the whole yeast is from Saccharomyces cerevisiae."],"number":12,"annotation":false,"title":false,"claim":true},{"lines":["The composition of claim 1, wherein the yeast vehicle is from Saccharomyces cerevisiae."],"number":13,"annotation":false,"title":false,"claim":true},{"lines":["A composition comprising:\n
a) a yeast vehicle; and\n
b) an HCV fusion protein consisting of SEQ ID NO:2, wherein expression of the HCV fusion protein is under the control of the promoter CUP1;\n
wherein the HCV fusion protein is expressed by the yeast vehicle; and\n
wherein the composition elicits an HCV NS3-specific immune response and an HCV Core-specific immune response."],"number":14,"annotation":false,"title":false,"claim":true},{"lines":["The composition of claim 14, further comprising at least one biological response modifier."],"number":15,"annotation":false,"title":false,"claim":true},{"lines":["The composition of claim 14, wherein the composition is formulated for injection."],"number":16,"annotation":false,"title":false,"claim":true},{"lines":["The composition of claim 14, wherein the yeast vehicle is a whole yeast."],"number":17,"annotation":false,"title":false,"claim":true},{"lines":["The composition of claim 17, wherein the whole yeast is killed."],"number":18,"annotation":false,"title":false,"claim":true},{"lines":["The composition of claim 17, wherein the whole yeast is heat-inactivated."],"number":19,"annotation":false,"title":false,"claim":true},{"lines":["The composition of claim 19, wherein the whole yeast is from Saccharomyces cerevisiae."],"number":20,"annotation":false,"title":false,"claim":true},{"lines":["The composition of claim 14, wherein the yeast vehicle is from Saccharomyces cerevisiae."],"number":21,"annotation":false,"title":false,"claim":true},{"lines":["A composition comprising:\n
a) a yeast vehicle; and\n
b) an HCV fusion protein consisting of SEQ ID NO:2;\n
wherein the HCV fusion protein is expressed by the yeast vehicle; and\n
wherein the composition elicits an HCV NS3-specific immune response and an HCV Core-specific immune response."],"number":22,"annotation":false,"title":false,"claim":true},{"lines":["The composition of claim 22, wherein the yeast vehicle is a whole yeast."],"number":23,"annotation":false,"title":false,"claim":true},{"lines":["The composition of claim 23, wherein the whole yeast is killed."],"number":24,"annotation":false,"title":false,"claim":true},{"lines":["The composition of claim 23, wherein the whole yeast is heat-inactivated."],"number":25,"annotation":false,"title":false,"claim":true},{"lines":["The composition of claim 25, wherein the whole yeast is from Saccharomyces cerevisiae."],"number":26,"annotation":false,"title":false,"claim":true},{"lines":["The composition of claim 22, wherein the yeast vehicle is from Saccharomyces cerevisiae."],"number":27,"annotation":false,"title":false,"claim":true}]}},"filters":{"npl":[],"notNpl":[],"applicant":[],"notApplicant":[],"inventor":[],"notInventor":[],"owner":[],"notOwner":[],"tags":[],"dates":[],"types":[],"notTypes":[],"j":[],"notJ":[],"fj":[],"notFj":[],"classIpcr":[],"notClassIpcr":[],"classNat":[],"notClassNat":[],"classCpc":[],"notClassCpc":[],"so":[],"notSo":[],"sat":[]},"sequenceFilters":{"s":"SEQIDNO","d":"ASCENDING","p":0,"n":10,"sp":[],"si":[],"len":[],"t":[],"loc":[]}}