Anti Aging Agents And Methods To Identify Them

Abstract

The present invention discloses novel mechanisms in the aging process and describes novel methods for high-throughput screening to identify, detect, and purify agents to be used for improving mitochondrial function, maintaining the cell cycle-arrested state in senescent and post mitotic cells, and thus preventing or treating age-related diseases or disorders associated with accelerated mitochondrial function loss, telomere dysfunction, and/or deterioration of the growth-arrested state. The present invention also discloses a number of compounds or compositions identified from this method. The present invention further provides the use of low doses of rapamycin or its analogs as a mimic of caloric restriction in preventing age-related diseases or disorders.


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Document History
  • Publication: Jul 23, 2013
  • Application: Apr 12, 2010
    US US 75838410 A
  • Priority: Apr 12, 2010
    US US 75838410 A
  • Priority: Apr 10, 2009
    US US 16831109 P
  • Priority: Apr 10, 2009
    US US 16833509 P

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