{"search_session":{},"preferences":{"l":"en","queryLanguage":"en"},"patentId":"152-899-520-514-401","frontPageModel":{"patentViewModel":{"ref":{"entityRefType":"PATENT","entityRefId":"152-899-520-514-401"},"entityMetadata":{"linkedIds":{"empty":true},"tags":[],"collections":[{"id":11855,"type":"PATENT","title":"University of Montpellier Patent Portfolio","description":"","access":"OPEN_ACCESS","displayAvatar":true,"attested":false,"itemCount":11808,"tags":[],"user":{"id":91044780,"username":"Cambialens","firstName":"","lastName":"","created":"2015-05-04T00:55:26.000Z","displayName":"Cambialens","preferences":"{\"usage\":\"public\",\"beta\":false}","accountType":"PERSONAL","isOauthOnly":false},"notes":[{"id":8467,"type":"COLLECTION","user":{"id":91044780,"username":"Cambialens","firstName":"","lastName":"","created":"2015-05-04T00:55:26.000Z","displayName":"Cambialens","preferences":"{\"usage\":\"public\",\"beta\":false}","accountType":"PERSONAL","isOauthOnly":false},"text":"
Search Applicants and Owners separately:univ* AND Montpellier. Select more for logical variants. Add to collection. Select all patents in the collection and expand by simple families. Add to collection. Total patents: 1289
Search Applicants and Owners separately:univ* AND Montpellier. Select more for logical variants. Add to collection. Select all patents in the collection and expand by simple families. Add to collection. Total patents: 1289
i) measuring an expression level of eleven genes in an endometrial biopsy sample from the patient, wherein the eleven genes are MFAP5, ANGPTL1, PROK1, NLF2, LAMB3, BCL2L10, CD68, TRPC4, SORCS1, FST and KRT80; and\n
ii) if at least one of the eleven genes is overexpressed, then a) concluding that the endometrium of the patient is receptive and b) proceeding with IVF procedures;\nor\n
iii) if none of the eleven genes is overexpressed, then c) concluding that the endometrium of the patient is not receptive and d) stopping IVF procedures."],"number":5,"annotation":false,"title":false,"claim":true},{"lines":["The method of claim 5, wherein said step of measuring is carried out by determining a quantity of mRNA associated with expression of said eleven genes, or determining a quantity of proteins encoded by said eleven genes."],"number":6,"annotation":false,"title":false,"claim":true},{"lines":["The method of claim 5, wherein all of said eleven genes are overexpressed."],"number":7,"annotation":false,"title":false,"claim":true},{"lines":["The method of claim 5, wherein said step of proceeding with IVF procedures includes a step of implanting an embryo."],"number":8,"annotation":false,"title":false,"claim":true},{"lines":["The method of claim 8, wherein the embryo is autologous."],"number":9,"annotation":false,"title":false,"claim":true},{"lines":["A method of obtaining a blastocyst, comprising the steps of\n
measuring an expression level of eleven genes in an endometrial biopsy sample from a patient, wherein the eleven genes are MFAP5, ANGPTL1, PROK1, NLF2, LAMB3, BCL2L10, CD68, TRPC4, SORCS1, FST and KRT80;\n
concluding that the endometrium of the patient is receptive if at least one of the eleven genes is overexpressed,\n
preparing competent endometrial cells from an endometrial explant from the patient;\n
coculturing the competent endometrial cells with an embryo to obtain a blastocyst."],"number":10,"annotation":false,"title":false,"claim":true},{"lines":["A method of in vitro fertilization (IVF), comprising the steps of\n
measuring an expression level of eleven genes in an endometrial biopsy sample from the patient, wherein the eleven genes are MFAP5, ANGPTL1, PROK1, NLF2, LAMB3, BCL2L10, CD68, TRPC4, SORCS1, FST and KRT80; and\n
concluding that the endometrium of the patient is receptive if at least one of the eleven genes is overexpressed,\n
preparing competent endometrial cells from an endometrial explant from the patient;\n
coculturing the competent endometrial cells with an embryo to obtain a blastocyst; and\n
implanting the blastocyst into the patient."],"number":11,"annotation":false,"title":false,"claim":true},{"lines":["An endometrial explant obtainable from an endometrium which has been considered as receptive by\n
i) measuring an expression level of eleven genes in an endometrial biopsy sample from the endometrium, wherein the eleven genes are MFAP5, ANGPTL1, PROK1, NLF2, LAMB3, BCL2L10, CD68, TRPC4, SORCS1, FST and KRT80; and\n
ii) if at least one of the eleven genes is overexpressed, then concluding that the endometrium is receptive."],"number":12,"annotation":false,"title":false,"claim":true},{"lines":["A kit comprising means for measuring the expression levels of eleven genes in an endometrial biopsy sample from a patient, wherein said genes are MFAP5, ANGPTL1, PROK1, NLF2, LAMB3, BCL2L10, CD68, TRPC4, SORCS1, FST and KRT80."],"number":13,"annotation":false,"title":false,"claim":true}]}},"filters":{"npl":[],"notNpl":[],"applicant":[],"notApplicant":[],"inventor":[],"notInventor":[],"owner":[],"notOwner":[],"tags":[],"dates":[],"types":[],"notTypes":[],"j":[],"notJ":[],"fj":[],"notFj":[],"classIpcr":[],"notClassIpcr":[],"classNat":[],"notClassNat":[],"classCpc":[],"notClassCpc":[],"so":[],"notSo":[],"sat":[]},"sequenceFilters":{"s":"SEQIDNO","d":"ASCENDING","p":0,"n":10,"sp":[],"si":[],"len":[],"t":[],"loc":[]}}