Use Of 2,5-dihydroxybenzenesulfonic Acid In The Manufacturing Of Medicines, Applicable To The Treatment Of Angiodependent Diseases


The invention relates to the use of 2,5-dihydroxybenzenesulfonic acid in the production of medicaments for the treatment of angiodependent diseases. More specifically, the invention relates to the use of the aforesaid compound and, in particular, the calcium and potassium salts thereof, for the treatment of two angiodependent diseases, which present a reduction in the apoptosis, namely cancer and psoriasis. The invention also discloses the antiproliferative, antimigratory, antiangiogenic and proapoptotic capacity of said family of compounds in non-quiescent cells. In addition, the invention details the potentiating effect of said compounds on known cytostatic medicines in the treatment of tumours and, specifically, on gliomas. The invention further relates to the therapeutic efficacy of said compounds, based on the combined antiproliferative, antiangiogenic and proapaptotic capacities thereof, in the treatment of chronic psoriatic plaques.

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Document History
  • Publication: May 7, 2013
  • Application: Jun 27, 2011
    US US 201113169781 A
  • Priority: Jun 27, 2011
    US US 201113169781 A
  • Priority: Aug 7, 2008
    US US 58816608 A
  • Priority: Feb 16, 2005
    ES ES 2005070017 W
  • Priority: Feb 17, 2004
    ES ES 200400371 A

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