{"search_session":{},"preferences":{"l":"en","queryLanguage":"en"},"patentId":"149-064-461-643-452","frontPageModel":{"patentViewModel":{"ref":{"entityRefType":"PATENT","entityRefId":"149-064-461-643-452"},"entityMetadata":{"linkedIds":{"empty":true},"tags":[],"collections":[{"id":10784,"type":"PATENT","title":"Purdue University - Patent Portfolio","description":"","access":"OPEN_ACCESS","displayAvatar":true,"attested":false,"itemCount":7369,"tags":[],"user":{"id":91044780,"username":"Cambialens","firstName":"","lastName":"","created":"2015-05-04T00:55:26.000Z","displayName":"Cambialens","preferences":"{\"usage\":\"public\",\"beta\":false}","accountType":"PERSONAL","isOauthOnly":false},"notes":[{"id":8254,"type":"COLLECTION","user":{"id":91044780,"username":"Cambialens","firstName":"","lastName":"","created":"2015-05-04T00:55:26.000Z","displayName":"Cambialens","preferences":"{\"usage\":\"public\",\"beta\":false}","accountType":"PERSONAL","isOauthOnly":false},"text":"
Search Applicants and Owners separately: \"Purdue Uni*\";
Select more for logical variants. Add to collection. Select all patents in the collection and expand by simple families. Add to collection. Total patents: 467
Search Applicants and Owners separately: \"Purdue Uni*\";
Select more for logical variants. Add to collection. Select all patents in the collection and expand by simple families. Add to collection. Total patents: 467
(a) generating a first charge on the molecule;\n
(b) changing the first charge on the molecule to a second charge; and\n
(c) changing the second charge on the molecule to a third charge;\n
where the second charge has the opposite polarity of the first charge, or the third charge has the opposite polarity of the second charge, or where the second charge has the opposite polarity of the first charge, and the third charge has the opposite polarity of the second charge."],"number":1,"annotation":false,"title":false,"claim":true},{"lines":["The process of claim 1, wherein the generating step includes generating a first charge on the molecule where the molecule is selected from the group consisting of proteins, peptides, nucleic acids, oligonucleotides, oligosaccharides, and carbohydrates."],"number":2,"annotation":false,"title":false,"claim":true},{"lines":["The process of claim 1, wherein the generating step includes generating a first charge on the molecule using a technique selected from the group consisting of plasma desorption ionization, field desorption ionization, electrohydrodynamic ionization, laser desorption ionization, matrix assisted laser desorption ionization, atmospheric pressure matrix assisted laser desorption ionization, electrospray ionization, nano-electrospray ionization, thermospray ionization, aerospray ionization, sonic spray ionization, fast atom bombardment, fast ion bombardment, secondary ion mass spectrometry, and massive cluster impact."],"number":3,"annotation":false,"title":false,"claim":true},{"lines":["The process of claim 1, wherein the changing step includes changing the first charge to a second charge, where the absolute value of the second charge is equal to or less than the absolute value of the first charge."],"number":4,"annotation":false,"title":false,"claim":true},{"lines":["The process of claim 1, wherein the changing step includes changing the first charge to a second charge, where the absolute value of the second charge is less than the absolute value of the first charge."],"number":5,"annotation":false,"title":false,"claim":true},{"lines":["The process of claim 1, wherein the changing step includes changing the first charge to a second charge by contacting the molecule with a multiply charged ionic compound having a plurality of charged groups."],"number":6,"annotation":false,"title":false,"claim":true},{"lines":["The process of claim 6, wherein plurality of charged groups is selected from the group consisting of ammonium groups, iminium groups, and protonated heteroaromatic groups."],"number":7,"annotation":false,"title":false,"claim":true},{"lines":["The process of claim 7, wherein the changing step includes changing the first charge to a second charge by contacting the molecule with a multiply charged dendrimer."],"number":8,"annotation":false,"title":false,"claim":true},{"lines":["The process of claim 6, wherein plurality of charged groups is selected from the group consisting of hydroxide groups, carboxylate groups, sulfonate groups, and phosphonate groups."],"number":9,"annotation":false,"title":false,"claim":true},{"lines":["The process of claim 9, wherein the changing step includes changing the first charge to a second charge by contacting the molecule with a multiply charged dendrimer."],"number":10,"annotation":false,"title":false,"claim":true},{"lines":["The process of claim 1, wherein the changing step includes changing the first charge to the second charge, where the molecule is in the gas phase."],"number":11,"annotation":false,"title":false,"claim":true},{"lines":["The process of claim 1, wherein the changing step includes changing the first charge to a second charge in an ion storage trap selected from the group consisting of quadrupole ion traps and linear ion traps."],"number":12,"annotation":false,"title":false,"claim":true},{"lines":["The process of claim 1, wherein the changing step includes changing the second charge to a third charge, where the absolute value of the third charge is equal to or greater than the absolute value of the second charge."],"number":13,"annotation":false,"title":false,"claim":true},{"lines":["The process of claim 1, wherein the changing step includes changing the second charge to a third charge by contacting the molecule with a multiply charged ionic compound having a plurality of charged groups."],"number":14,"annotation":false,"title":false,"claim":true},{"lines":["The process of claim 14, wherein the plurality of charged groups is selected from the group consisting of ammonium groups, iminium groups, and protonated heteroaromatic groups."],"number":15,"annotation":false,"title":false,"claim":true},{"lines":["The process of claim 15, wherein the changing step includes changing the first charge to a second charge by contacting the molecule with a multiply charged dendrimer."],"number":16,"annotation":false,"title":false,"claim":true},{"lines":["The process of claim 14, wherein the plurality of charged groups is selected from the group consisting of hydroxide groups, carboxylate groups, sulfonate groups, and phosphonate groups."],"number":17,"annotation":false,"title":false,"claim":true},{"lines":["The process of claim 17, wherein the changing step includes changing the first charge to a second charge by contacting the molecule with a multiply charged dendrimer."],"number":18,"annotation":false,"title":false,"claim":true},{"lines":["The process of claim 1, wherein the changing step includes changing the second charge to a third charge in an ion storage trap selected from the group consisting of quadrupole ion traps and linear ion traps."],"number":19,"annotation":false,"title":false,"claim":true},{"lines":["The process of claim 1, wherein the changing step includes changing the second charge to a third charge, where the second charge is the opposite polarity of the third charge."],"number":20,"annotation":false,"title":false,"claim":true},{"lines":["The process of claim 20, wherein the changing step includes changing the second charge to a third charge, where the second charge is a negative charge, by contacting the molecule with a compound selected from the group consisting of poly(alkyleneimine) dendrimers and poly(alkyleneamine) dendrimers."],"number":21,"annotation":false,"title":false,"claim":true},{"lines":["The process of claim 20, wherein the changing step includes changing the second charge to the third charge, where the second charge is a positive charge, by contacting the molecule with a compound selected from the group consisting of poly(alkylenecarboxylic acid) dendrimers and poly(alkylenesulfonic acid) dendrimers."],"number":22,"annotation":false,"title":false,"claim":true},{"lines":["The process of claim 1, further comprising the step of concentrating the third charge using ion parking."],"number":23,"annotation":false,"title":false,"claim":true},{"lines":["The process of claim 1, further comprising detecting the molecule or a fragment thereof using tandem mass spectrometry."],"number":24,"annotation":false,"title":false,"claim":true},{"lines":["The process of claim 24, further comprising concentrating the charge states of the molecule or a fragment thereof prior to the detecting step."],"number":25,"annotation":false,"title":false,"claim":true},{"lines":["The process of claim 1, further comprising lowering the absolute value of the third charge by at least one using an atmospheric sampling glow discharge ionization source."],"number":26,"annotation":false,"title":false,"claim":true},{"lines":["The process of claim 26, wherein the lowering step is performed prior to the detecting step."],"number":27,"annotation":false,"title":false,"claim":true},{"lines":["The process of claim 1, further comprising identifying the molecule or a fragment thereof."],"number":28,"annotation":false,"title":false,"claim":true},{"lines":["A process for analyzing a molecule by mass spectrometry, comprising:\n
(a) generating a first charge on the molecule;\n
(b) changing the first charge on the molecule to a second charge having the opposite polarity of the first charge; and\n
(c) changing the second charge on the molecule to a third charge having the opposite polarity of the second charge."],"number":29,"annotation":false,"title":false,"claim":true},{"lines":["The process of claim 29, wherein the step of changing the first charge and the step of changing the second charge are performed contemporaneously, by contacting the molecule having the first charge, or a fragment thereof, with a first multiply charged ionic compound, and a second multiply charged ionic compound, where the first ionic compound and the second ionic compound have charges of opposite polarity."],"number":30,"annotation":false,"title":false,"claim":true},{"lines":["A process for analyzing a molecule by mass spectrometry, comprising generating a first charge on the molecule having an absolute value equal to or greater than one; changing the first charge on the molecule to a second charge having an absolute value of one, by contacting the molecule with a first multiply charged ionic compound; and changing the second charge on the molecule to a third charge having an absolute value greater than one, by contacting the molecule with a second multiply charged ionic compound."],"number":31,"annotation":false,"title":false,"claim":true},{"lines":["The process of claim 31, wherein the generating step includes generating the first charge by plasma desorption ionization, field desorption ionization, electrohydrodynamic ionization, laser desorption ionization, matrix assisted laser desorption ionization, atmospheric pressure matrix assisted laser desorption ionization, electrospray ionization, nano-electrospray ionization, thermospray ionization, aerospray ionization, sonic spray ionization, fast atom bombardment, fast ion bombardment, secondary ion mass spectrometry, or massive cluster impact."],"number":32,"annotation":false,"title":false,"claim":true}]}},"filters":{"npl":[],"notNpl":[],"applicant":[],"notApplicant":[],"inventor":[],"notInventor":[],"owner":[],"notOwner":[],"tags":[],"dates":[],"types":[],"notTypes":[],"j":[],"notJ":[],"fj":[],"notFj":[],"classIpcr":[],"notClassIpcr":[],"classNat":[],"notClassNat":[],"classCpc":[],"notClassCpc":[],"so":[],"notSo":[],"sat":[]},"sequenceFilters":{"s":"SEQIDNO","d":"ASCENDING","p":0,"n":10,"sp":[],"si":[],"len":[],"t":[],"loc":[]}}