Cox1-interacting Proteins And Use Thereof

Abstract

Protein complexes are provided comprising COX1 and one or more proteins selected from the group consisting of THR S14 and Opa1. The protein complexes are useful in screening assays for identifying compounds effective in modulating the protein complexes and in treating and/or preventing diseases and disorders associated with COX1 and its interacting partner proteins. In addition, methods of detecting the protein complexes and modulating the functions and activities of the protein complexes or interacting members thereof are also provided.


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Document History
  • Publication: Nov 28, 2006
  • Application: Mar 18, 2002
    US US 10050302 A
  • Priority: Mar 18, 2002
    US US 10050302 A
  • Priority: Mar 19, 2001
    US US 27701301 P

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