Methods For Regulating Bud-hypha Transitions And Camp Levels In Candida Albicans

Abstract

The infection of a mammalian host by a microorganism can be prevented or treated through the alteration of the C. albicans homologue of the high affinity phosphodiesterase, PDE2, gene and/or the adenylate cyclase-associated protein gene. These methods may be used in the identification, prevention or treatment of microbial infection of mammalian hosts such as immunocompromised or immunosuppressed humans, for example, those having AIDS or undergoing transplantation or anti-cancer therapy.


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Document History
  • Publication: Sep 18, 2007
  • Application: Sep 29, 2003
    US US 67207403 A
  • Priority: Sep 29, 2003
    US US 67207403 A
  • Priority: Mar 9, 2001
    US US 80177401 A

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