{"search_session":{},"preferences":{"l":"en","queryLanguage":"en"},"patentId":"144-547-834-917-888","frontPageModel":{"patentViewModel":{"ref":{"entityRefId":"144-547-834-917-888","entityRefType":"PATENT"},"entityMetadata":{"linkedIds":{"empty":true},"tags":[],"collections":[{"id":8878,"type":"PATENT","title":"Kyoto University Patent Portfolio","description":"","access":"OPEN_ACCESS","displayAvatar":true,"attested":false,"itemCount":10470,"tags":[],"user":{"id":91044780,"username":"Cambialens","firstName":"","lastName":"","created":"2015-05-04T00:55:26.000Z","displayName":"Cambialens","preferences":"{\"usage\":\"public\",\"beta\":false}","accountType":"PERSONAL","isOauthOnly":false},"notes":[{"id":8212,"type":"COLLECTION","user":{"id":91044780,"username":"Cambialens","firstName":"","lastName":"","created":"2015-05-04T00:55:26.000Z","displayName":"Cambialens","preferences":"{\"usage\":\"public\",\"beta\":false}","accountType":"PERSONAL","isOauthOnly":false},"text":"
Search Applicants and Owners separately = \"Kyoto University\", \"Kyoto Univ\", \" Univ Kyoto\", \" University Kyoto\", \"Kyot* Univ*\", \"Univ* Kyot*\".
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Search Applicants and Owners separately = \"Kyoto University\", \"Kyoto Univ\", \" Univ Kyoto\", \" University Kyoto\", \"Kyot* Univ*\", \"Univ* Kyot*\".
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(a) the step of bringing into contact with each other a canine somatic cell and a nuclear reprogramming factor,\n
(b) the step of culturing the cell in a medium containing one or more substance(s) selected from the group consisting of a mitogen-activated protein kinase kinase inhibitor, an activin receptor-like kinase inhibitor, a glycogen synthase kinase inhibitor, a L-type calcium channel agonist and a DNA methylation inhibitor, and a leukemia inhibitory factor."],"number":1,"annotation":false,"claim":true,"title":false},{"lines":["The process according to claim 1, wherein the more than one substances are a mitogen-activated protein kinase kinase inhibitor, an activin receptor-like kinase inhibitor and a glycogen synthase kinase inhibitor; or a L-type calcium channel agonist and a DNA methylation inhibitor."],"number":2,"annotation":false,"claim":true,"title":false},{"lines":["The process according to claim 1, wherein the nuclear reprogramming factor is Oct3/4, Sox2 and Klf4."],"number":3,"annotation":false,"claim":true,"title":false},{"lines":["The process according to claim 1, wherein the nuclear reprogramming factor is Oct3/4, Sox2, Klf4 and c-Myc."],"number":4,"annotation":false,"claim":true,"title":false},{"lines":["The process according to claim 1, wherein the activin receptor-like kinase inhibitor is an activin receptor-like kinase 5 inhibitor."],"number":5,"annotation":false,"claim":true,"title":false},{"lines":["The process according to claim 1, wherein the glycogen synthase kinase inhibitor is a glycogen synthase kinase 3β inhibitor."],"number":6,"annotation":false,"claim":true,"title":false},{"lines":["The process according to claim 1, wherein the medium for the step (b) further contains a histone deacetylase inhibitor."],"number":7,"annotation":false,"claim":true,"title":false},{"lines":["The process according to claim 7, wherein the histone deacetylase inhibitor is valproic acid or a salt thereof."],"number":8,"annotation":false,"claim":true,"title":false},{"lines":["The process according to claim 1, wherein the medium for the step (b) further contains a basic fibroblast growth factor."],"number":9,"annotation":false,"claim":true,"title":false},{"lines":["The process according to claim 1, wherein the cultivation in the step (b) is performed within 48 hours after contact with the nuclear reprogramming factor."],"number":10,"annotation":false,"claim":true,"title":false},{"lines":["The process according to claim 1, wherein the cultivation is performed on feeder cells after the elapse of 3 to 5 weeks after contact with the nuclear reprogramming factor."],"number":11,"annotation":false,"claim":true,"title":false},{"lines":["A canine pluripotent stem cell of somatic cell derivation possessing pluripotency and a potential for self-replication."],"number":12,"annotation":false,"claim":true,"title":false},{"lines":["The cell according to claim 12, wherein the reprogramming gene is genetically stably present."],"number":13,"annotation":false,"claim":true,"title":false},{"lines":["The cell according to claim 13, wherein the reprogramming gene is at least one selected from among Oct3/4, Sox2, Klf4 and c-Myc."],"number":14,"annotation":false,"claim":true,"title":false},{"lines":["A canine iPS cell produced by the process according to claim 1."],"number":15,"annotation":false,"claim":true,"title":false},{"lines":["A canine somatic cell differentiated from the cell according to claim 12."],"number":16,"annotation":false,"claim":true,"title":false}]}},"filters":{"npl":[],"notNpl":[],"applicant":[],"notApplicant":[],"inventor":[],"notInventor":[],"owner":[],"notOwner":[],"tags":[],"dates":[],"types":[],"notTypes":[],"j":[],"notJ":[],"fj":[],"notFj":[],"classIpcr":[],"notClassIpcr":[],"classNat":[],"notClassNat":[],"classCpc":[],"notClassCpc":[],"so":[],"notSo":[],"sat":[]},"sequenceFilters":{"s":"SEQIDNO","d":"ASCENDING","p":0,"n":10,"sp":[],"si":[],"len":[],"t":[],"loc":[]}}