{"search_session":{},"preferences":{"l":"en","queryLanguage":"en"},"patentId":"143-224-214-730-884","frontPageModel":{"patentViewModel":{"ref":{"entityRefType":"PATENT","entityRefId":"143-224-214-730-884"},"entityMetadata":{"linkedIds":{"empty":true},"tags":[],"collections":[{"id":10710,"type":"PATENT","title":"University of Colorado Boulder Patent Portforlio","description":"","access":"OPEN_ACCESS","displayAvatar":true,"attested":false,"itemCount":7179,"tags":[],"user":{"id":91044780,"username":"Cambialens","firstName":"","lastName":"","created":"2015-05-04T00:55:26.000Z","displayName":"Cambialens","preferences":"{\"usage\":\"public\",\"beta\":false}","accountType":"PERSONAL","isOauthOnly":false},"notes":[{"id":8227,"type":"COLLECTION","user":{"id":91044780,"username":"Cambialens","firstName":"","lastName":"","created":"2015-05-04T00:55:26.000Z","displayName":"Cambialens","preferences":"{\"usage\":\"public\",\"beta\":false}","accountType":"PERSONAL","isOauthOnly":false},"text":"
Search Applicants and Owners separately:\"University Colorado\" \"univ* Colorado\"
Select more for logical variants. Add to collection. Select all patents in the collection and expand by simple families. Add to collection. Total patents: 4836
Search Applicants and Owners separately:\"University Colorado\" \"univ* Colorado\"
Select more for logical variants. Add to collection. Select all patents in the collection and expand by simple families. Add to collection. Total patents: 4836
a) detecting the level of E-cadherin polynucleotides in a sample of tumor cells from said patient;\n
b) comparing said level to a level of E-cadherin polynucleotides in a sample of tumor cells from a subject having lung cancer that is resistant to gefitinib; and,\n
c) selecting the patient as being predicted to benefit from therapeutic administration of an EGFR inhibitor, selected from the group consisting of gefitinib and erlotinib, if the level of E-cadherin polynucleotides in the sample of tumor cells from said patient is higher than the level of E-cadherin polynucleotides in the sample of tumor cells from the subject that is resistant to gefitinib."],"number":1,"annotation":false,"title":false,"claim":true},{"lines":["The method of claim 1, comprising detecting expression of the E-cadherin polynucleotide represented by SEQ ID NO:3."],"number":2,"annotation":false,"title":false,"claim":true},{"lines":["The method of claim 1, wherein the EGFR inhibitor is gefitinib."],"number":3,"annotation":false,"title":false,"claim":true},{"lines":["The method of claim 1, wherein the EGFR inhibitor is erlotinib."],"number":4,"annotation":false,"title":false,"claim":true}]}},"filters":{"npl":[],"notNpl":[],"applicant":[],"notApplicant":[],"inventor":[],"notInventor":[],"owner":[],"notOwner":[],"tags":[],"dates":[],"types":[],"notTypes":[],"j":[],"notJ":[],"fj":[],"notFj":[],"classIpcr":[],"notClassIpcr":[],"classNat":[],"notClassNat":[],"classCpc":[],"notClassCpc":[],"so":[],"notSo":[],"sat":[]},"sequenceFilters":{"s":"SEQIDNO","d":"ASCENDING","p":0,"n":10,"sp":[],"si":[],"len":[],"t":[],"loc":[]}}