Ubiquitin Conjugating Enzymes

Abstract

The present invention relates to drug screening assays which provide a systematic and practical approach for the identification of candidate agents able to inhibit ubiquitin-mediated degradation of a cell-cycle regulatory protein, such as p53, p27, myc, fos, MAT alpha 2, or cyclins. The invention further relates to novel ubiquitin-conjugating enzymes, and uses related thereto.


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Owners (US)
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Document History
  • Publication: May 30, 2000
  • Application: Dec 17, 1996
    US US 76794296 A
  • Priority: Dec 17, 1996
    US US 76794296 A
  • Priority: Jun 7, 1995
    US US 48666395 A
  • Priority: Sep 13, 1994
    US US 30552094 A
  • Priority: May 27, 1994
    US US 25079594 A
  • Priority: May 23, 1994
    US US 24790494 A
  • Priority: Jan 4, 1994
    US US 17693794 A

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