Integration Of Very Short Electric Pulses For Minimally To Noninvasive Electroporation


The present invention provides methods, devices, and systems for in vivo treatment of cell proliferative disorders. The invention can be used to treat solid tumors, such as brain tumors. The methods rely on non-thermal irreversible electroporation (IRE) or supra-poration to cause cell death in treated tumors. In embodiments, the methods comprise the integration of ultra-short electric pulses, both temporally and spatially, to achieve the desired modality of cell death.

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Document History
  • Publication: Jan 6, 2015
  • Application: Apr 9, 2010
    US US 75790110 A
  • Priority: Apr 9, 2010
    US US 75790110 A
  • Priority: Dec 11, 2009
    US US 28561809 P
  • Priority: Apr 9, 2009
    US US 16799709 P

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