Methods For Identifying Inhibitors Of Neuronal Degeneration

Abstract

The present invention concerns methods and means for identifying inhibitors of neuronal degeneration, and their use in the treatment of neurodegenerative disorders. In particular the invention concerns methods and means for identifying inhibitors of neuronal degeneration or cell death by taking advantage of the involvement of presenilin (PS) and Par-4 in NF-kappaB activation.


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Document History
  • Publication: Dec 27, 2005
  • Application: Jan 4, 2001
    US US 75494901 A
  • Priority: Jan 4, 2001
    US US 75494901 A
  • Priority: Jan 10, 2000
    US US 17520000 P

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