Glycolate Oxidase Inhibitors For The Treatment Of Disease

  • Published: Jul 4, 2019
  • Earliest Priority: Dec 29 2017
  • Family: 3
  • Cited Works: 12
  • Cited by: 1
  • Cites: 0
  • Additional Info: Cited Works Full text
Abstract

Described herein are compounds, methods of making such compounds, pharmaceutical compositions and medicaments containing such compounds, and methods of using such compounds to treat or prevent diseases or disorders associated with the enzyme glycolate oxidase (GO). Such diseases or disorders include, for example, disorders of glyoxylate metabolism, including primary hyperoxaluria, that are associated with production of excessive amounts of oxalate.


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